WTAP

Gene Symbol	WTAP
Entrez Gene	9589
Alt Symbol	Mum2
Species	Human
Gene Type	protein-coding
Description	Wilms tumor 1 associated protein
Other Description	PNAS-132|WT1-associated protein|Wilms' tumour 1-associating protein|female-lethal(2)D homolog|hFL(2)D|pre-mRNA-splicing regulator WTAP|putative pre-mRNA splicing regulator female-lethal(2D)|wilms tumor 1-associating protein
Swissprots	Q9BYJ7 Q15007 Q5TCL9 Q9H4E2 Q96T28 Q5TCL8
Accessions	EAW47622 EAW47623 EAW47624 EAW47625 EAW47626 EAW47627 EAW47628 Q15007 AA706250 AF277190 AAK07548 AF374416 AAK54764 AJ276706 CAC10188 AK127822 BAG54579 AK131393 AK290854 BAF83543 AL583911 CAC29495 BC000383 AAH00383 BC004432 AAH04432 BC028180 BC069192 AAH69192 BE906617 BG702882 BQ778248 BQ948913 BX387163 CN284477 CR627456 CAH10537 D14661 BAA03495 DA138013 DA561768 HQ447554 ADQ32040 XM_011536264 XP_011534566 NM_001270531 NP_001257460 NM_001270532 NP_001257461 NM_001270533 NP_001257462 NM_004906 NP_004897 NM_152857 NP_690596 NM_152858 NP_690597
Function	Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. {ECO:0000269|PubMed:12444081, ECO:0000269|PubMed:17088532, ECO:0000269|PubMed:17095724, ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location	Nucleus, nucleolus. Nucleus speckle.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:11001926}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WTAP 293T Cell Transient Overexpression Lysate(Denatured) - H00009589-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

WTAP overexpression lysate - LY407186 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WTAP overexpression lysate - LY407187 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WTAP overexpression lysate - LY417661 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WTAP overexpression lysate - LY430230 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

WTAP 293 Cell Lysate - 404150 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Disease Tumor

WTAP 293 Cell Lysate - 408267 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Disease Tumor

WTAP Overexpression Lysate (Denatured) - H00009589-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

WTAP Overexpression Lysate (Native) - NBL1-17889 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WTAP Overexpression Lysate (Native) - NBP2-05288 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WTAP Overexpression Lysate (Native) - NBP2-05287 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

WTAP Over-expression Lysate Product - GWB-D22A40 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

WTAP Over-expression Lysate Product - GWB-3D2C67 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

WTAP Overexpression Lysate (Native) - NBP2-10000 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human WTAP Knockdown Stable Cell Line - CSC-DC017540 from Creative biogene Category Cell Line Species Human

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