WTAP

Gene Symbol	WTAP
Entrez Gene	9589
Alt Symbol	Mum2
Species	Human
Gene Type	protein-coding
Description	Wilms tumor 1 associated protein
Other Description	PNAS-132|WT1-associated protein|Wilms' tumour 1-associating protein|female-lethal(2)D homolog|hFL(2)D|pre-mRNA-splicing regulator WTAP|putative pre-mRNA splicing regulator female-lethal(2D)|wilms tumor 1-associating protein
Swissprots	Q9BYJ7 Q15007 Q5TCL9 Q9H4E2 Q96T28 Q5TCL8
Accessions	EAW47622 EAW47623 EAW47624 EAW47625 EAW47626 EAW47627 EAW47628 Q15007 AA706250 AF277190 AAK07548 AF374416 AAK54764 AJ276706 CAC10188 AK127822 BAG54579 AK131393 AK290854 BAF83543 AL583911 CAC29495 BC000383 AAH00383 BC004432 AAH04432 BC028180 BC069192 AAH69192 BE906617 BG702882 BQ778248 BQ948913 BX387163 CN284477 CR627456 CAH10537 D14661 BAA03495 DA138013 DA561768 HQ447554 ADQ32040 XM_011536264 XP_011534566 NM_001270531 NP_001257460 NM_001270532 NP_001257461 NM_001270533 NP_001257462 NM_004906 NP_004897 NM_152857 NP_690596 NM_152858 NP_690597
Function	Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. {ECO:0000269|PubMed:12444081, ECO:0000269|PubMed:17088532, ECO:0000269|PubMed:17095724, ECO:0000269|PubMed:24316715, ECO:0000269|PubMed:24407421}.
Subcellular Location	Nucleus, nucleolus. Nucleus speckle.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:11001926}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WTAP full length protein - ab198661 from Abcam Category Protein Source E. coli Species Human

WTAP Antibody Blocking Peptide - LS-E4544 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human WTAP Protein - H00009589-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human WTAP Protein - H00009589-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

WTAP-Antibody-C-term-Blocking-Peptide - BP16885b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human WTAP GST tag protein - orb84737 from Biorbyt Category Protein Prices $417.00, $859.00 Sizes 20 μg, 100 μg Source E. coli Species Human

WTAP - H00009589-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

WTAP - H00009589-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

WTAP - H00009589-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

WTAP - H00009589-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

WTAP fusion protein - Ag0259 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Wilms Tumor 1 Associated Protein, T7-tagged - WTAP-3014H from Creative Biomart Category Protein

Recombinant Human WTAP, T7 -tagged - WTAP-31529TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human WTAP, GST tagged - WTAP-7047H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human WTAP, GST-tagged - WTAP-3744H from Creative Biomart Category Protein Source E.coli Species Human

Human WTAP Protein (GST Tag) - 12018-H09E-100 from Sino Biological Category Protein Prices $348.00, $348.00 Sizes 20 µg, 100 µg Source E. coli Species Human

WTAP (H351) Peptide - BS2062P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Pre-mRNA-splicing regulator WTAP(WTAP) - CSB-YP618970HU CSB-EP618970HU CSB-BP618970HU CSB-MP618970HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

WTAP (transcript variant 1) - TP309632 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

WTAP (transcript variant 2) - TP323046 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

WTAP (transcript variant 3) - TP323099 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Pre-mRNA-splicing regulator WTAP (WTAP), Recombinant Protein - MBS1421559 from MyBioSource Category Protein Prices $1,170.00, $1,170.00, $1,395.00, $1,395.00, $1,870.00, $1,870.00, $2,335.00, $2,335.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human WTAP Protein (GST tag) - PKSH030933 from Elabscience Category Protein Source E. coli Species Human

Recombinant Wilms Tumor 1 Associated Protein (WTAP) - RPC245Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Wilms Tumor 1 Associated Protein (WTAP) - RPC245Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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