Gene Symbol | CDKAL1 |
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Entrez Gene | 54901 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | CDK5 regulatory subunit associated protein 1-like 1 |
Other Description | tRNA-t(6)A37 methylthiotransferase|threonylcarbamoyladenosine tRNA methylthiotransferase |
Swissprots | Q6P385 Q9NXB3 A8K6S0 Q5VV42 Q6ZR27 |
Accessions | CAK32475 EAW55425 EAW55426 EAW55427 Q5VV42 AK000349 BAA91102 AK024151 AK074342 AK128546 BAC87494 AK291735 BAF84424 AK309457 AK310219 BC064145 AAH64145 BC121020 AAI21021 BC121021 AAI21022 XM_006715128 XP_006715191 XM_011514718 XP_011513020 XM_011514719 XP_011513021 XR_926265 XR_926266 XR_926267 NM_017774 NP_060244 |
Function | Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. {ECO:0000269|PubMed:20584901}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:23048041}; Single-pass membrane protein {ECO:0000269|PubMed:23048041}. Note=Is a tail-anchored protein that exploits the TCR40 pathway for insertion into the endoplasmic reticulum. |
Tissue Specificity | Expressed in pancreatic islets. {ECO:0000269|PubMed:23048041}. |
Human CDKAL1 full length protein - ab132667 from Abcam
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Human CDKAL1 peptide - ab74018 from Abcam
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Human CDKAL1 peptide - ab74019 from Abcam
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CDKAL1 Antibody Blocking Peptide - LS-E26584 from LifeSpan Bioscience
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Recombinant Human CDKAL1 Protein - H00054901-P01 from Novus Biologicals
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CDKAL1 blocking peptide - GTX88493-PEP from GeneTex
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CDKAL1 Peptide - AC21-1420-P from Abcore
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CDKAL1 - H00054901-P01-10 from Acris Antibodies
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CDKAL1 - H00054901-P01-25 from Acris Antibodies
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CDKAL1 Peptide - 42-028P from ProSci
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CDKAL1 fusion protein - Ag19060 from Proteintech Group
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CDKAL1 fusion protein - ag17837 from Proteintech Group
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Recombinant Human CDKAL1, His-tagged - CDKAL1-11058H from Creative Biomart
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CDKAL1 - TP324917 from Acris Antibodies
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CDKAL1, Peptide - MBS426383 from MyBioSource
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CDKAL1 Recombinant Protein Antigen - NBP1-83660PEP from Novus Biologicals
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CDKAL1-Antibody-N-term-Blocking-Peptide - BP5021a from Abgent, a WuXi AppTec company
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CDKAL1 Peptide, Human - M34GP02884H from Creative Peptides
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Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1), Recombinant Protein - MBS7084402 from MyBioSource
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Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1), Recombinant Protein - MBS7011215 from MyBioSource
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CDKAL1 Immunizing peptide - orb55016 from Biorbyt
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