| Gene Symbol | AIF1 |
|---|---|
| Entrez Gene | 199 |
| Alt Symbol | AIF-1, IBA1, IRT-1, IRT1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | allograft inflammatory factor 1 |
| Other Description | allograft inflammatory factor-1 splice variant Hara-1|interferon gamma responsive transcript|ionized calcium-binding adapter molecule 1|protein G1 |
| Swissprots | A8K406 Q9UKS9 P55008 Q9UIV4 O43904 |
| Accessions | AAD18087 BAB63392 CAA75060 CAA75061 CAA75062 EAX03442 EAX03443 EAX03444 EAX03445 EAX03446 EAX03447 P55008 AF088038 AF299327 AAG39110 AF299329 AAG39112 AK290771 BAF83460 BC009474 AAH09474 CB215777 CD521003 CR542153 CAG46950 D86438 BAA13088 DB502939 EF070981 EF070982 ABK35646 EF070983 ABK35647 EU832665 ACE87756 EU832744 ACE87076 JQ782414 AFL46387 JQ782415 AFL46388 U19713 AAB05003 U49392 AAA92457 U95213 AAC24422 XM_005248870 XP_005248927 XM_005248871 XP_005248928 XM_005272778 XP_005272835 XM_005272779 XP_005272836 XM_005274924 XP_005274981 XM_005274925 XP_005274982 XM_005275220 XP_005275277 XM_005275221 XP_005275278 XM_005275356 XP_005275413 XM_005275357 XP_005275414 XM_005275515 XP_005275572 XM_005275516 XP_005275573 NM_001623 NP_001614 NM_004847 NP_004838 NM_032955 NP_116573 |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. {ECO:0000269|PubMed:15117732, ECO:0000269|PubMed:16049345, ECO:0000269|PubMed:18699778}. |
| Subcellular Location | Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
| Tissue Specificity | Detected in T-lymphocytes and peripheral blood mononuclear cells. {ECO:0000269|PubMed:16049345}. |
Human AIF1 Gene cDNA Clone - orb143646 from Biorbyt
|
||||||||
Human-AIF1-cDNA-Clone - DC02667 from Abgent, a WuXi AppTec company
|
||||||||
AIF1 - MBS1273921 from MyBioSource
|
||||||||
Human AIF1 cDNA clone(NM_032955.1) - CDFG006482 from Creative Biomart
|
||||||||
Human AIF1 cDNA clone(NM_001623.3) - CDFH000523 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_001623.3) - CDCL153445 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_004847.3) - CDCL153446 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_001623.3) - CDCL153447 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_001623.3) - CDCR281160 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_001623.3) - CDCR281161 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_004847.3) - CDCR288989 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_004847.3) - CDCR288990 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_032955.1) - CDCR313148 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_032955.1) - CDCR313149 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_032955.1) - CDCR313150 from Creative Biomart
|
||||||||
Human AIF1 ORF Clone(NM_004847.3) - CDCR288989 from Creative biogene
|
||||||||
Human AIF1 ORF Clone(NM_032955.1) - CDCR313148 from Creative biogene
|
||||||||
Human AIF1 ORF clone (NM_001623.3) - CDCR025996 from Creative biogene
|
||||||||
Human AIF1 ORF Clone (BC009474) - CDCS410341 from Creative biogene
|
||||||||
Human AIF1 ORF clone (BC009474) - CDCB159276 from Creative biogene
|
||||||||
Human AIF1 cDNA Clone(NM_032955.1) - CDFG006482 from Creative biogene
|
||||||||
Human AIF1 cDNA Clone(NM_001623.3) - CDFH000523 from Creative biogene
|
||||||||
Human AIF1 Gene cDNA clone plasmid - HG14227-G from Sino Biological
|