AIF1

Gene Symbol	AIF1
Entrez Gene	199
Alt Symbol	AIF-1, IBA1, IRT-1, IRT1
Species	Human
Gene Type	protein-coding
Description	allograft inflammatory factor 1
Other Description	allograft inflammatory factor-1 splice variant Hara-1|interferon gamma responsive transcript|ionized calcium-binding adapter molecule 1|protein G1
Swissprots	A8K406 Q9UKS9 P55008 Q9UIV4 O43904
Accessions	AAD18087 BAB63392 CAA75060 CAA75061 CAA75062 EAX03442 EAX03443 EAX03444 EAX03445 EAX03446 EAX03447 P55008 AF088038 AF299327 AAG39110 AF299329 AAG39112 AK290771 BAF83460 BC009474 AAH09474 CB215777 CD521003 CR542153 CAG46950 D86438 BAA13088 DB502939 EF070981 EF070982 ABK35646 EF070983 ABK35647 EU832665 ACE87756 EU832744 ACE87076 JQ782414 AFL46387 JQ782415 AFL46388 U19713 AAB05003 U49392 AAA92457 U95213 AAC24422 XM_005248870 XP_005248927 XM_005248871 XP_005248928 XM_005272778 XP_005272835 XM_005272779 XP_005272836 XM_005274924 XP_005274981 XM_005274925 XP_005274982 XM_005275220 XP_005275277 XM_005275221 XP_005275278 XM_005275356 XP_005275413 XM_005275357 XP_005275414 XM_005275515 XP_005275572 XM_005275516 XP_005275573 NM_001623 NP_001614 NM_004847 NP_004838 NM_032955 NP_116573
Function	Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. {ECO:0000269|PubMed:15117732, ECO:0000269|PubMed:16049345, ECO:0000269|PubMed:18699778}.
Subcellular Location	Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Tissue Specificity	Detected in T-lymphocytes and peripheral blood mononuclear cells. {ECO:0000269|PubMed:16049345}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Iba1 full length protein - ab173043 from Abcam Category Protein Source E. coli Species Human

Human Iba1 full length protein - ab105593 from Abcam Category Protein Source E. coli Species Human

Human Iba1 full length protein - ab117478 from Abcam Category Protein Source E. coli Species Human

Human Iba1 peptide - ab23067 from Abcam Category Peptide Species Human

Human Iba1 peptide - ab48051 from Abcam Category Peptide Species Human

AIF1 / IBA1 Blocking Peptide - LS-E217 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AIF1 / IBA1 Antibody Blocking Peptide - LS-E25347 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AIF1 / IBA1 Antibody Blocking Peptide - LS-E26061 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AIF1 / IBA1 Antibody Blocking Peptide - LS-E26101 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human AIF-1/Iba1 Protein - H00000199-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human AIF-1/Iba1 Protein - NBP1-51074 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

AIF1-Antibody-N-term-Blocking-Peptide - BP10449a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AIF1-Antibody-C-term-Blocking-peptide - BP11202b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Iba1 (isoform 1 and 3) blocking peptide - GTX89792-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Pig, Rat

Iba1 (isoform 3) blocking peptide - GTX89367-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Iba1 (isoforms 1 + 3) blocking peptide - GTX89048-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

AIF1 Protein (OPPA02072) - OPPA02072 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human IBA1 protein (His Tag) - orb139028 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human AIF1 protein - orb80254 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

Human AIF1 protein - orb244007 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human AIF1 R protein - orb163471 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source E. coli Species Human

AIF1 protein (His tag) - 80R-1764 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Human AIF1 Protein - abx065221 from Abbexa Category Protein Source E.coli Species Human

Iba1 Peptide - AC21-0175-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Iba1 Peptide - AC21-0889-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

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