AIF1

Gene Symbol AIF1
Entrez Gene 199
Alt Symbol AIF-1, IBA1, IRT-1, IRT1
Species Human
Gene Type protein-coding
Description allograft inflammatory factor 1
Other Description allograft inflammatory factor-1 splice variant Hara-1|interferon gamma responsive transcript|ionized calcium-binding adapter molecule 1|protein G1
Swissprots A8K406 Q9UKS9 P55008 Q9UIV4 O43904
Accessions AAD18087 BAB63392 CAA75060 CAA75061 CAA75062 EAX03442 EAX03443 EAX03444 EAX03445 EAX03446 EAX03447 P55008 AF088038 AF299327 AAG39110 AF299329 AAG39112 AK290771 BAF83460 BC009474 AAH09474 CB215777 CD521003 CR542153 CAG46950 D86438 BAA13088 DB502939 EF070981 EF070982 ABK35646 EF070983 ABK35647 EU832665 ACE87756 EU832744 ACE87076 JQ782414 AFL46387 JQ782415 AFL46388 U19713 AAB05003 U49392 AAA92457 U95213 AAC24422 XM_005248870 XP_005248927 XM_005248871 XP_005248928 XM_005272778 XP_005272835 XM_005272779 XP_005272836 XM_005274924 XP_005274981 XM_005274925 XP_005274982 XM_005275220 XP_005275277 XM_005275221 XP_005275278 XM_005275356 XP_005275413 XM_005275357 XP_005275414 XM_005275515 XP_005275572 XM_005275516 XP_005275573 NM_001623 NP_001614 NM_004847 NP_004838 NM_032955 NP_116573
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. {ECO:0000269|PubMed:15117732, ECO:0000269|PubMed:16049345, ECO:0000269|PubMed:18699778}.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Tissue Specificity Detected in T-lymphocytes and peripheral blood mononuclear cells. {ECO:0000269|PubMed:16049345}.

Iba1 CRISPR/Cas9 KO Plasmid (h) - sc-400513 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 HDR Plasmid (h) - sc-400513-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 Double Nickase Plasmid (h) - sc-400513-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 Double Nickase Plasmid (h2) - sc-400513-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 CRISPR Activation Plasmid (h) - sc-400513-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 CRISPR Activation Plasmid (h2) - sc-400513-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 Lentiviral Activation Particles (h) - sc-400513-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 Lentiviral Activation Particles (h2) - sc-400513-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Iba1 siRNA (h) - sc-43857 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Iba1 shRNA Plasmid (h) - sc-43857-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Iba1 shRNA (h) Lentiviral Particles - sc-43857-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AIF-1/Iba1 RNAi - H00000199-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

AIF-1/Iba1 RNAi - H00000199-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AIF-1/Iba1 RNAi - H00000199-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN2980 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2980 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00156 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00156

AIF1 siRNA (Human) - CRH0138 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AIF1 - MBS8212438 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AIF1 (NM_001623.3) - SHH233894 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AIF1(NM_001623.3) - SHG048265 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human AIF1(NM_032955.1) - SHG048331 from Creative biogene

Category siRNA
Species Reactivities Human

AIF1 shRNA Plasmid (Human) - CHH0138 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AIF1 miRNA 3'UTR clone - MiUTR1H-00254 from Creative biogene

Species Reactivities Human

AIF1 miRNA 3'UTR clone - MiUTR1H-00255 from Creative biogene

Species Reactivities Human
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