HSD3B7

Gene Symbol	HSD3B7
Entrez Gene	80270
Alt Symbol	CBAS1, PFIC4, SDR11E3
Species	Human
Gene Type	protein-coding
Description	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Other Description	3 beta-hydroxy-delta 5-C27-steroid oxidoreductase|3 beta-hydroxysteroid dehydrogenase type 7|3 beta-hydroxysteroid dehydrogenase type VII|3-beta-HSD VII|3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase|C(27)-3BETA-HSD|c(27) 3-beta-HSD|cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase|short chain dehydrogenase/reductase family 11E, member 3
Swissprots	Q9BSN9 Q9H2F3 Q96M28
Accessions	EAW52183 Q9H2F3 AF277719 AAG37824 AK057436 BAB71486 AK290950 BAF83639 AK292068 BAF84757 BC004929 AAH04929 BM744211 CA413388 DB336146 EU176407 ABW03858 EU176408 ABW03859 XM_005255601 XP_005255658 XM_011545960 XP_011544262 XM_011545961 XP_011544263 XM_011545962 XP_011544264 NM_001142777 NP_001136249 NM_001142778 NP_001136250 NM_025193 NP_079469
Function	The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways	Primary bile acid biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HSD3B7 full length protein - ab133011 from Abcam Category Protein Source Wheat germ Species Human

Human HSD3B7 protein fragment - ab127110 from Abcam Category Protein Source E. coli Species Human

HSD3B7 Antibody Blocking Peptide - LS-E18033 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HSD3B7 Protein - H00080270-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HSD3B7 Recombinant Protein - H00080270-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

HSD3B7 Blocking Peptide - 33R-7574 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

3-beta HSD7 / HSD3B7 - H00080270-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

3-beta HSD7 / HSD3B7 - H00080270-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

3-beta HSD7 / HSD3B7 - H00080270-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

3-beta HSD7 / HSD3B7 - H00080270-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HSD3B7 fusion protein - ag0755 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human HSD3B7, GST-tagged - HSD3B7-13966H from Creative Biomart Category Protein Source E.coli Species Human

HSD3B7 Protein - NBP2-14103PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

HSD3B7 Blocking Peptide - abx061682 from Abbexa Category Peptide

HSD3B7-Antibody-Center-Blocking-peptide - BP5233c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSD3B7 Peptide, Human - M34GP07288H from Creative Peptides Category Peptide Source Synthetic. Species Human

HSD3B7 Blocking Peptide - CBP7072 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

3 beta-hydroxysteroid dehydrogenase type 7 (HSD3B7), Recombinant Protein - MBS7016807 from MyBioSource Category Protein Prices $1,175.00, $2,165.00, $3,370.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

HSD3B7 peptide - orb339289 from Biorbyt Category Peptide Prices $213.00, $417.00 Sizes 1 mg, 5 mg

HSD3B7 Recombinant Protein Antigen - NBP2-56368PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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