HSD3B7

Gene Symbol HSD3B7
Entrez Gene 80270
Alt Symbol CBAS1, PFIC4, SDR11E3
Species Human
Gene Type protein-coding
Description hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Other Description 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase|3 beta-hydroxysteroid dehydrogenase type 7|3 beta-hydroxysteroid dehydrogenase type VII|3-beta-HSD VII|3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase|C(27)-3BETA-HSD|c(27) 3-beta-HSD|cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase|short chain dehydrogenase/reductase family 11E, member 3
Swissprots Q9BSN9 Q9H2F3 Q96M28
Accessions EAW52183 Q9H2F3 AF277719 AAG37824 AK057436 BAB71486 AK290950 BAF83639 AK292068 BAF84757 BC004929 AAH04929 BM744211 CA413388 DB336146 EU176407 ABW03858 EU176408 ABW03859 XM_005255601 XP_005255658 XM_011545960 XP_011544262 XM_011545961 XP_011544263 XM_011545962 XP_011544264 NM_001142777 NP_001136249 NM_001142778 NP_001136250 NM_025193 NP_079469
Function The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways Primary bile acid biosynthesis

3β-HSD7 (H-137) - sc-98636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

3β-HSD7 (Y-15) - sc-83775 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

3β-HSD7 (A-13) - sc-83772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HSD3B7 antibody - ab190223 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human kidney tissue labeling HSD3B7 with ab190223 at 10 µg/ml.

Anti-HSD3B7 antibody - ab203256 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded rat lung tissue sections labeling HSD3B7 with ab203256 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-HSD3B7 antibody - ab104093 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD3B7 antibody (ab104093) at 1/100 dilution + Mouse NIH3T3 cell line lysates at 35 µg

Anti-HSD3B7 antibody - ab112532 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HSD3B7 antibody (ab112532) at 1/500 dilutionLane 1 : Human fetal lung lysateLane 2 : Human fetal colon lysate

Anti-HSD3B7 antibody - ab136846 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD3B7 antibody (ab136846) at 1/500 dilution + Jurkat cell lysate at 30 µg

Anti-HSD3B7 Antibody (aa111-266) - LS-C178582 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD3B7 Antibody (aa108-157) - LS-C292069 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD3B7 Antibody (aa107-156) - LS-C116378 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HSD3B7 antibody LS-C116378 Western blot of OVCAR-3 cell lysate.

Anti-HSD3B7 Antibody (aa111-266) - LS-C178581 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD3B7 Antibody (aa121-170) IHC-plus™ - LS-B9680 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD3B7 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9680 concentration 10 ug/ml.

HSD3B7 Antibody - NBP1-56994 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HSD3B7 Antibody [NBP1-56994] - OVCAR-3 cell lysate, concentration 0.2-1 ug/ml.

HSD3B7 Antibody - NBP2-14103 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: HSD3B7 Antibody [NBP2-14103] - Staining of human cell line Hep G2 shows localization to lipid droplets.

HSD3B7 Antibody - H00080270-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

HSD3B7 Polyclonal Antibody - bs-2366R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Antigen: bs-2366P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;\\nTMB staining;\\nRead the data in MicroplateReader by 450

Anti-HSD3B7 antibody produced in rabbit - SAB2105735 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HSD3B7: <B>Cat. No. SAB2105735</B>: HSD3B7 in OVCAR-3 cell lysates with HSD3B7 antibody at 1.0 μg/mL.

Anti-HSD3B7 antibody produced in rabbit - HPA050521 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HSD3B7:<B>Cat. No. HPA050521</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in renal tubules.

HSD3B7 antibody - middle region (ARP49934_P050) - ARP49934_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HSD3B7 Antibody (OAAF03106) - OAAF03106 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

HSD3B7 Antibody (OAAF06503) - OAAF06503 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

HSD3B7 antibody - orb77927 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded fetal heart showing cytoplasmic staining using HSD3B7 antibody

HSD3B7 antibody - orb77926 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal lung and colon lysate using HSD3B7 antibody

HSD3B7 antibody - 70R-17829 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Search more