HSD3B7

Gene Symbol HSD3B7
Entrez Gene 80270
Alt Symbol CBAS1, PFIC4, SDR11E3
Species Human
Gene Type protein-coding
Description hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Other Description 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase|3 beta-hydroxysteroid dehydrogenase type 7|3 beta-hydroxysteroid dehydrogenase type VII|3-beta-HSD VII|3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase|C(27)-3BETA-HSD|c(27) 3-beta-HSD|cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase|short chain dehydrogenase/reductase family 11E, member 3
Swissprots Q9BSN9 Q9H2F3 Q96M28
Accessions EAW52183 Q9H2F3 AF277719 AAG37824 AK057436 BAB71486 AK290950 BAF83639 AK292068 BAF84757 BC004929 AAH04929 BM744211 CA413388 DB336146 EU176407 ABW03858 EU176408 ABW03859 XM_005255601 XP_005255658 XM_011545960 XP_011544262 XM_011545961 XP_011544263 XM_011545962 XP_011544264 NM_001142777 NP_001136249 NM_001142778 NP_001136250 NM_025193 NP_079469
Function The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways Primary bile acid biosynthesis

3β-HSD7 siRNA (h) - sc-72402 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

3β-HSD7 shRNA Plasmid (h) - sc-72402-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

3β-HSD7 shRNA (h) Lentiviral Particles - sc-72402-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSD3B7 RNAi - H00080270-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU091621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10335 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10335 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HSD3B7 siRNA (Human) - CRJ2832 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSD3B7 - MBS8232921 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HSD3B7 (NM_025193.3) - SHH315325 from Creative biogene

Category siRNA
Species Reactivities Human

Human HSD3B7 siRNA - orb273333 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSD3B7 shRNA Plasmid (Human) - CHJ2832 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HSD3B7 miRNA 3'UTR clone - MiUTR3H-09457 from Creative biogene

Species Reactivities Human

HSD3B7 miRNA 3'UTR clone - MiUTR3H-09458 from Creative biogene

Species Reactivities Human

HSD3B7 miRNA 3'UTR clone - MiUTR3H-09459 from Creative biogene

Species Reactivities Human
Search more