GSPT2

Gene Symbol	GSPT2
Entrez Gene	23708
Alt Symbol	ERF3B, GST2
Species	Human
Gene Type	protein-coding
Description	G1 to S phase transition 2
Other Description	eukaryotic peptide chain release factor GTP-binding subunit ERF3B|eukaryotic peptide chain release factor subunit 3b
Swissprots	Q9H909 Q9NVY0 Q9NY44 Q8IYD1
Accessions	EAW62898 Q8IYD1 AI191874 AJ251548 CAB91089 AK001303 BAA91612 AK023155 AK225671 AK298868 BAG60988 BC036077 AAH36077 BF514488 DA712335 DB173006 NM_018094 NP_060564
Function	Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. {ECO:0000269|PubMed:11524954, ECO:0000269|PubMed:15987998, ECO:0000269|PubMed:17562865}.
Subcellular Location	Cytoplasm {ECO:0000305}.
Tissue Specificity	Highly expressed in IUCC stage II colorectal cancer (CRC). {ECO:0000269|PubMed:16721809}.
Top Pathways	mRNA surveillance pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human eRF3B/GSPT2 full length protein - ab161753 from Abcam Category Protein Source Wheat germ Species Human

GSPT2 Antibody Blocking Peptide - LS-E10251 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GSPT2 Antibody Blocking Peptide - LS-E19998 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GSPT2 Protein - H00023708-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ERF3B-Antibody-Center-Blocking-Peptide - BP9663c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GSPT2 Blocking Peptide - 33R-5685 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GSPT2 Blocking Peptide - 33R-3163 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GSPT2 / ERF3B - H00023708-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GSPT2 / ERF3B - H00023708-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GSPT2 fusion protein - ag3641 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Eukaryotic peptide chain release factor GTP-binding subunit ERF3B(GSPT2) - CSB-YP812896HU CSB-EP812896HU CSB-BP812896HU CSB-MP812896HU from Cusabio Category Peptide Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GSPT2 / ERF3B - TP306259 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

GSPT2 Recombinant Protein Antigen - NBP1-91971PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GSPT2 Peptide, Human - M34GP06705H from Creative Peptides Category Peptide Source Synthetic. Species Human

Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (GSPT2), Recombinant Protein - MBS1481968 from MyBioSource Category Protein Prices $1,425.00, $1,425.00, $1,655.00, $1,655.00, $2,410.00, $2,410.00, $2,855.00, $2,855.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more