GSPT2

Gene Symbol GSPT2
Entrez Gene 23708
Alt Symbol ERF3B, GST2
Species Human
Gene Type protein-coding
Description G1 to S phase transition 2
Other Description eukaryotic peptide chain release factor GTP-binding subunit ERF3B|eukaryotic peptide chain release factor subunit 3b
Swissprots Q9H909 Q9NVY0 Q9NY44 Q8IYD1
Accessions EAW62898 Q8IYD1 AI191874 AJ251548 CAB91089 AK001303 BAA91612 AK023155 AK225671 AK298868 BAG60988 BC036077 AAH36077 BF514488 DA712335 DB173006 NM_018094 NP_060564
Function Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. {ECO:0000269|PubMed:11524954, ECO:0000269|PubMed:15987998, ECO:0000269|PubMed:17562865}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Highly expressed in IUCC stage II colorectal cancer (CRC). {ECO:0000269|PubMed:16721809}.
Top Pathways mRNA surveillance pathway

Anti-eRF3B/GSPT2 antibody - ab103005 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-eRF3B/GSPT2 antibody (ab103005) at 1/100 dilution + 293 cell line lysates at 35 µg

Anti-eRF3B/GSPT2 antibody - ab84180 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-eRF3B/GSPT2 antibody (ab84180) at 1 µg/ml + MCF7 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-eRF3B/GSPT2 antibody - ab103086 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-eRF3B/GSPT2 antibody (ab103086) at 1 µg/ml + ACHN Cell Lysate at 10 µg

Anti-eRF3B/GSPT2 antibody [2G9] - ab119049 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G9
All lanes : Anti-eRF3B/GSPT2 antibody [2G9] (ab119049) at 1/2000 dilutionLane 1 : HEK293T lysate transfected with pCMV6-ENTRY control cDNA Lane 2 : HEK293T lysate transfected with pCMV6-ENTRY eRF3B/GSPT2 cDNA Lysates/proteins at 5 µg per lane.

Anti-GSPT2 Antibody (aa216-245, AP) - LS-C235021 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa216-245, APC) - LS-C235022 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa216-245, Biotin) - LS-C235023 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa216-245, PE) - LS-C235026 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa216-245, FITC) - LS-C235024 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa216-245, Azide-free, HRP) - LS-C249925 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa223-253) - LS-C321169 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GSPT2 Antibody (aa216-245) - LS-C167802 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ERF3B Antibody western blot of 293 cell line and mouse stomach tissue lysates (35 ug/lane). The ERF3B antibody detected the ERF3B protein (arrow).

Anti-GSPT2 Antibody (aa144-193) - LS-C102620 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GSPT2 antibody LS-C102620 Western blot of MCF7 cell lysate.

Anti-GSPT2 Antibody (clone 2G9) - LS-C173045 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G9
Anti-GSPT2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GSPT2.

GSPT2 Antibody (2G9) - NBP2-00873 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G9
Western Blot: GSPT2 Antibody (2G9) [NBP2-00873] - Analysis of extracts (10ug) from 2 different cell lines by using anti-GSPT2 monoclonal antibody.(1:200)

GSPT2 Antibody - NBP1-91971 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GSPT2 Antibody [NBP1-91971] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

GSPT2 Antibody - NBP1-57646 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GSPT2 Antibody [NBP1-57646] - ACHN cell lysate, concentration 0.2-1 ug/ml.

Anti-GSPT2 antibody produced in rabbit - HPA044769 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GSPT2: <B>Cat. No. HPA044769</B>: Immunohistochemical staining of human rectum shows moderate cytoplasmic positivity in glandular cells.

Anti-GSPT2 (148-158) antibody produced in rabbit - SAB1101267 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-GSPT2 (148-158) (RB): <B>Cat. No. SAB1101267</B>: Immunofluorescence of HUVEC cells using GSPT2 (148-158) (RB), Cat. No. SAB1101267 (red) at a 1:400 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-GSPT2 antibody produced in rabbit - SAB2100979 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GSPT2: <B>Cat. No.SAB2100979</B>: GSPT2 in MCF7 cell lysate with GSPT2 antibody at 1.0 μg/mL.

ANTI-ERF3B (CENTER) antibody produced in rabbit - SAB1306070 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ERF3B (Center): <B>Cat. No. SAB1306070</B>: ERF3B Antibody (Center) western blot analysis in 293 cell line and Mouse stomach tissue lysates (35 μg/lane).

GSPT2 antibody - N-terminal region (ARP55356_P050) - ARP55356_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GSPT2 antibody - middle region (ARP55357_P050) - ARP55357_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ERF3B-Antibody-Center - AP9663c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ERF3B Antibody (Center) (Cat. #AP9663c) western blot analysis in 293 cell line and mouse stomach tissue lysates (35ug/lane).This demonstrates the ERF3B antibody detected the ERF3B protein (arrow).

GSPT2 Antibody - middle region (OAAB06260) - OAAB06260 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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