GSPT2

Gene Symbol GSPT2
Entrez Gene 23708
Alt Symbol ERF3B, GST2
Species Human
Gene Type protein-coding
Description G1 to S phase transition 2
Other Description eukaryotic peptide chain release factor GTP-binding subunit ERF3B|eukaryotic peptide chain release factor subunit 3b
Swissprots Q9H909 Q9NVY0 Q9NY44 Q8IYD1
Accessions EAW62898 Q8IYD1 AI191874 AJ251548 CAB91089 AK001303 BAA91612 AK023155 AK225671 AK298868 BAG60988 BC036077 AAH36077 BF514488 DA712335 DB173006 NM_018094 NP_060564
Function Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. {ECO:0000269|PubMed:11524954, ECO:0000269|PubMed:15987998, ECO:0000269|PubMed:17562865}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Highly expressed in IUCC stage II colorectal cancer (CRC). {ECO:0000269|PubMed:16721809}.
Top Pathways mRNA surveillance pathway

eRF3b CRISPR/Cas9 KO Plasmid (h) - sc-411779 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b HDR Plasmid (h) - sc-411779-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b Double Nickase Plasmid (h) - sc-411779-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b Double Nickase Plasmid (h2) - sc-411779-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b CRISPR Activation Plasmid (h) - sc-411779-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b CRISPR Activation Plasmid (h2) - sc-411779-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b Lentiviral Activation Particles (h) - sc-411779-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b Lentiviral Activation Particles (h2) - sc-411779-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eRF3b siRNA (h) - sc-91280 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eRF3b shRNA Plasmid (h) - sc-91280-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

eRF3b shRNA (h) Lentiviral Particles - sc-91280-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GSPT2 RNAi - H00023708-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU111251 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU147061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9728 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9728 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GSPT2 siRNA (Human) - CRH8439 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GSPT2 - MBS8215132 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GSPT2 (NM_018094.4) - SHH308506 from Creative biogene

Category siRNA
Species Reactivities Human

GSPT2 shRNA Plasmid (Human) - CHH8439 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GSPT2 miRNA 3'UTR clone - MiUTR3H-02769 from Creative biogene

Species Reactivities Human
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