ELOVL7

Gene Symbol	ELOVL7
Entrez Gene	79993
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ELOVL fatty acid elongase 7
Other Description	3-keto acyl-CoA synthase ELOVL7|ELOVL FA elongase 7|ELOVL family member 7, elongation of long chain fatty acids|elongation of very long chain fatty acids protein 7|very-long-chain 3-oxoacyl-CoA synthase 7
Swissprots	Q9NT66 A1L3X0 Q9H5D0 Q589T3
Accessions	A1L3X0 EAW55001 EAW55002 AB181393 BAD93238 AI769834 AK027216 BAB15697 AL137506 CAB70777 BC094792 BC130310 AAI30311 BC130312 AAI30313 BC144257 DA247166 HQ258375 ADR83129 XM_005248606 XP_005248663 XM_005248607 XP_005248664 XM_006714695 XP_006714758 XM_011543651 XP_011541953 NM_001104558 NP_001098028 NM_001297617 NP_001284546 NM_001297618 NP_001284547 NM_024930 NP_079206
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:19826053, ECO:0000269|PubMed:20937905, ECO:0000269|PubMed:21959040}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity	Expressed in most tissues except heart and skeletal muscle. {ECO:0000269|PubMed:20937905}.
Top Pathways	Fatty acid elongation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ELOVL7 Antibody Blocking Peptide - LS-E4220 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELOVL7 Antibody Blocking Peptide - LS-E30880 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ELOVL7 Recombinant Protein - H00079993-G01-10ug from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

ELOVL7-Antibody-C-term-Blocking-Peptide - BP16487b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELOVL7 Peptide - GTX85201-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

ELOVL7 Blocking Peptide - 33R-5651 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ELOVL7 Control Peptide - AP30312CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ELOVL7 Peptide - 5641P from ProSci Category Peptide Species Human

ELOVL7 Protein - NBP1-93926PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ELOVL7 Peptide, Human - M34GP04881H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human ELOVL7 Protein - H00079993-G01 from Novus Biologicals Category Protein Prices $519.00 Sizes 2 µg Species Human

Elongation of very long chain fatty acids protein 7 (ELOVL7), Recombinant Protein - MBS964907 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Elongation of very long chain fatty acids protein 7 (ELOVL7), Recombinant Protein - MBS7014230 from MyBioSource Category Protein Prices $1,095.00, $2,080.00, $3,290.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

ELOVL7 fusion protein - Ag25008 from Proteintech Group Category Protein Source E. coli -derived, PET30a Species Human

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