ELOVL7

Gene Symbol ELOVL7
Entrez Gene 79993
Alt Symbol -
Species Human
Gene Type protein-coding
Description ELOVL fatty acid elongase 7
Other Description 3-keto acyl-CoA synthase ELOVL7|ELOVL FA elongase 7|ELOVL family member 7, elongation of long chain fatty acids|elongation of very long chain fatty acids protein 7|very-long-chain 3-oxoacyl-CoA synthase 7
Swissprots Q9NT66 A1L3X0 Q9H5D0 Q589T3
Accessions A1L3X0 EAW55001 EAW55002 AB181393 BAD93238 AI769834 AK027216 BAB15697 AL137506 CAB70777 BC094792 BC130310 AAI30311 BC130312 AAI30313 BC144257 DA247166 HQ258375 ADR83129 XM_005248606 XP_005248663 XM_005248607 XP_005248664 XM_006714695 XP_006714758 XM_011543651 XP_011541953 NM_001104558 NP_001098028 NM_001297617 NP_001284546 NM_001297618 NP_001284547 NM_024930 NP_079206
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:19826053, ECO:0000269|PubMed:20937905, ECO:0000269|PubMed:21959040}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity Expressed in most tissues except heart and skeletal muscle. {ECO:0000269|PubMed:20937905}.
Top Pathways Fatty acid elongation

ELOVL7 CRISPR/Cas9 KO Plasmid (h) - sc-418315 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 HDR Plasmid (h) - sc-418315-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 Double Nickase Plasmid (h) - sc-418315-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 Double Nickase Plasmid (h2) - sc-418315-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 CRISPR Activation Plasmid (h) - sc-418315-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 CRISPR Activation Plasmid (h2) - sc-418315-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 Lentiviral Activation Particles (h) - sc-418315-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 Lentiviral Activation Particles (h2) - sc-418315-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELOVL7 siRNA (h) - sc-62273 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELOVL7 shRNA Plasmid (h) - sc-62273-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELOVL7 shRNA (h) Lentiviral Particles - sc-62273-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU156091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7826 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7826 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ELOVL7 siRNA (Human) - CRJ2713 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELOVL7 - MBS8213815 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ELOVL7 (NM_024930.2) - SHH285317 from Creative biogene

Category siRNA
Species Reactivities Human

Human ELOVL7 siRNA - orb273214 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELOVL7 shRNA Plasmid (Human) - CHJ2713 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ELOVL7 miRNA 3'UTR clone - MiUTR1H-03207 from Creative biogene

Species Reactivities Human
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