ELOVL7

Gene Symbol	ELOVL7
Entrez Gene	79993
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ELOVL fatty acid elongase 7
Other Description	3-keto acyl-CoA synthase ELOVL7|ELOVL FA elongase 7|ELOVL family member 7, elongation of long chain fatty acids|elongation of very long chain fatty acids protein 7|very-long-chain 3-oxoacyl-CoA synthase 7
Swissprots	Q9NT66 A1L3X0 Q9H5D0 Q589T3
Accessions	A1L3X0 EAW55001 EAW55002 AB181393 BAD93238 AI769834 AK027216 BAB15697 AL137506 CAB70777 BC094792 BC130310 AAI30311 BC130312 AAI30313 BC144257 DA247166 HQ258375 ADR83129 XM_005248606 XP_005248663 XM_005248607 XP_005248664 XM_006714695 XP_006714758 XM_011543651 XP_011541953 NM_001104558 NP_001098028 NM_001297617 NP_001284546 NM_001297618 NP_001284547 NM_024930 NP_079206
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:19826053, ECO:0000269|PubMed:20937905, ECO:0000269|PubMed:21959040}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity	Expressed in most tissues except heart and skeletal muscle. {ECO:0000269|PubMed:20937905}.
Top Pathways	Fatty acid elongation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ELOVL7 (H-50) - sc-134919 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

ELOVL7 (N-17) - sc-55642 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ELOVL7 (V-25) - sc-133545 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-ELOVL7 antibody - ab106633 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ELOVL7 antibody - ab129589 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (N-Terminus) IHC-plus™ - LS-B4637 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273, AP) - LS-C234927 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273, APC) - LS-C234928 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273, Biotin) - LS-C234930 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273, FITC) - LS-C234931 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (N-Terminus) - LS-C82579 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273, PE) - LS-C234935 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273, Azide-free, HRP) - LS-C249903 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa243-273) - LS-C321099 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 Antibody (aa244-273) - LS-C167740 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

ELOVL7 Antibody - NBP1-93926 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ELOVL7 Antibody - NBP1-91349 from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 antibody produced in rabbit - HPA036337 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ELOVL7 antibody produced in rabbit - SAB3500390 from Sigma-Aldrich Prices $348.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

ELOVL7 antibody - N-terminal region (ARP49908_T100) - ARP49908_T100 from Aviva Systems Biology Prices $229.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ELOVL7-Antibody-C-term - AP16487b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

ELOVL7 antibody - GTX85201 from GeneTex Prices $319.00 Sizes 100 μg Host Rabbit Clonality Polyclonal

ELOVL7 Antibody - C-terminal region (OAAB11903) - OAAB11903 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

ELOVL7 antibody - orb75377 from Biorbyt Prices $723.00 Sizes 100 μg Host Rabbit Clonality Polyclonal

ELOVL7 antibody - 70R-1788 from Fitzgerald Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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