| Gene Symbol |
SLCO1A2
|
| Entrez Gene |
6579
|
| Alt Symbol |
OATP, OATP-A, OATP1A2, SLC21A3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier organic anion transporter family, member 1A2
|
| Other Description |
OATP-1|organic anion transporting polypeptide A|organic anion-transporting polypeptide 1|sodium-independent organic anion transporter|solute carrier family 21 (organic anion transporter), member 3|solute carrier family 21 member 3|solute carrier organic anion transporter family member 1A2
|
| Swissprots |
Q9UGP7 Q9UL38 P46721
|
| Accessions |
CAB64372 CAB97006 EAW96422 EAW96423 EAW96424 EAW96425 P46721 AF085224 AAD52694 AF279784 AAG30037 AK296044 BAG58808 AK316249 BAH14620 BC042452 AAH42452 BC144256 BX093727 DA184882 DA216595 DA220201 DA322842 DA412674 U21943 AAA87732 XM_005253474 XP_005253531 XM_005253477 XP_005253534 XM_011520818 XP_011519120 XM_011520819 XP_011519121 XM_011520820 XP_011519122 XM_011520821 XP_011519123 NM_021094 NP_066580 NM_134431 NP_602307 NM_005075
|
| Function |
Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin. {ECO:0000250, ECO:0000269|PubMed:17301733}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Bile secretion
|
![Western Blot: SLCO1A2 Overexpression Lysate (Adult Normal) [NBL1-16201] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLCO1A2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10190_SLCO1A2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16201-img0002.jpg)
![Western Blot: SLCO1A2 Overexpression Lysate (Adult Normal) [NBL1-16202] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SLCO1A2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5670_SLCO1A2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16202-img0002.jpg)