Gene Symbol | SLCO1A2 |
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Entrez Gene | 6579 |
Alt Symbol | OATP, OATP-A, OATP1A2, SLC21A3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier organic anion transporter family, member 1A2 |
Other Description | OATP-1|organic anion transporting polypeptide A|organic anion-transporting polypeptide 1|sodium-independent organic anion transporter|solute carrier family 21 (organic anion transporter), member 3|solute carrier family 21 member 3|solute carrier organic anion transporter family member 1A2 |
Swissprots | Q9UGP7 Q9UL38 P46721 |
Accessions | CAB64372 CAB97006 EAW96422 EAW96423 EAW96424 EAW96425 P46721 AF085224 AAD52694 AF279784 AAG30037 AK296044 BAG58808 AK316249 BAH14620 BC042452 AAH42452 BC144256 BX093727 DA184882 DA216595 DA220201 DA322842 DA412674 U21943 AAA87732 XM_005253474 XP_005253531 XM_005253477 XP_005253534 XM_011520818 XP_011519120 XM_011520819 XP_011519121 XM_011520820 XP_011519122 XM_011520821 XP_011519123 NM_021094 NP_066580 NM_134431 NP_602307 NM_005075 |
Function | Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin. {ECO:0000250, ECO:0000269|PubMed:17301733}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Bile secretion |
SLCO1A2 / OATP Antibody Blocking Peptide - LS-E16140 from LifeSpan Bioscience
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SLCO1A2 / OATP Antibody Blocking Peptide - LS-E16141 from LifeSpan Bioscience
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SLCO1A2 Blocking Peptide - 33R-1268 from Fitzgerald
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SLCO1A2 fusion protein - ag13566 from Proteintech Group
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Recombinant Human SLCO1A2, His-tagged - SLCO1A2-2791H from Creative Biomart
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OATP1 Blocking Peptide - CBP2080 from Cohesion Biosciences
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OATP1 (N286) Peptide - BS3952P from Bioworld Technology
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SLCO1A2 Protein - abx163557 from Abbexa
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SLCO1A2 Peptide, Human - M34GP14670H from Creative Peptides
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SLCO1A2 Recombinant Protein Antigen - NBP2-56965PEP from Novus Biologicals
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Solute carrier organic anion transporter family member 1A2 (SLCO1A2), Recombinant Protein - MBS957230 from MyBioSource
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