Gene Symbol | SLCO1A2 |
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Entrez Gene | 6579 |
Alt Symbol | OATP, OATP-A, OATP1A2, SLC21A3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier organic anion transporter family, member 1A2 |
Other Description | OATP-1|organic anion transporting polypeptide A|organic anion-transporting polypeptide 1|sodium-independent organic anion transporter|solute carrier family 21 (organic anion transporter), member 3|solute carrier family 21 member 3|solute carrier organic anion transporter family member 1A2 |
Swissprots | Q9UGP7 Q9UL38 P46721 |
Accessions | CAB64372 CAB97006 EAW96422 EAW96423 EAW96424 EAW96425 P46721 AF085224 AAD52694 AF279784 AAG30037 AK296044 BAG58808 AK316249 BAH14620 BC042452 AAH42452 BC144256 BX093727 DA184882 DA216595 DA220201 DA322842 DA412674 U21943 AAA87732 XM_005253474 XP_005253531 XM_005253477 XP_005253534 XM_011520818 XP_011519120 XM_011520819 XP_011519121 XM_011520820 XP_011519122 XM_011520821 XP_011519123 NM_021094 NP_066580 NM_134431 NP_602307 NM_005075 |
Function | Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin. {ECO:0000250, ECO:0000269|PubMed:17301733}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Bile secretion |
OATP-A (E-7) - sc-365007 from Santa Cruz Biotechnology
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OATP-A (H-55) - sc-48744 from Santa Cruz Biotechnology
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OATP-A (E-15) - sc-18427 from Santa Cruz Biotechnology
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OATP-A (C-15) - sc-18428 from Santa Cruz Biotechnology
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Oatp3 (H-82) - sc-292101 from Santa Cruz Biotechnology
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Anti-SLCO1A2 antibody - ab110392 from Abcam
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Anti-SLCO1A2 antibody - ab105124 from Abcam
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Anti-SLCO1A2 / OATP Antibody (C-Terminus) - LS-C17012 from LifeSpan Bioscience
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Anti-SLCO1A2 / OATP Antibody (C-Terminus) - LS-C17013 from LifeSpan Bioscience
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Anti-SLCO1A2 / OATP Antibody (aa451-500) - LS-C116246 from LifeSpan Bioscience
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Anti-SLCO1A2 / OATP Antibody (aa251-300) - LS-C120414 from LifeSpan Bioscience
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Anti-SLCO1A2 / OATP Antibody (aa201-250) - LS-C40428 from LifeSpan Bioscience
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SLCO1A2 Antibody - NBP1-59658 from Novus Biologicals
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SLCO1A2 Antibody - NBP1-56236 from Novus Biologicals
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Anti-SLCO1A2 antibody produced in rabbit - SAB4502814 from Sigma-Aldrich
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Anti-SLCO1A2 antibody produced in rabbit - AV43898 from Sigma-Aldrich
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Anti-SLCO1A2 antibody produced in rabbit - SAB2105539 from Sigma-Aldrich
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SLCO1A2 antibody - middle region (ARP43898_P050) - ARP43898_P050 from Aviva Systems Biology
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SLCO1A2 antibody - middle region (ARP43899_P050) - ARP43899_P050 from Aviva Systems Biology
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SLCO1A2 Antibody (OAAF04324) - OAAF04324 from Aviva Systems Biology
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SLCO1A2 antibody - 70R-8581 from Fitzgerald
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SLCO1A2 antibody - orb227047 from Biorbyt
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SLCO1A2 antibody - 70R-6567 from Fitzgerald
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Anti-OATP1 (N286) - 31-B3952 from ARP American Research Products
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SLCO1A2 Antibody - 29-918 from ProSci
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