SNRPD1

Gene Symbol SNRPD1
Entrez Gene 6632
Alt Symbol HsT2456, SMD1, SNRPD, Sm-D1
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein D1 polypeptide 16kDa
Other Description Sm-D autoantigen|small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene|small nuclear ribonucleoprotein Sm D1|snRNP core protein D1
Swissprots B5BTZ1 P62314
Accessions AAA85339 EAX01130 P62314 AB451227 BAG70041 AB451350 BAG70164 AJ577268 CAE11897 BC001721 AAH01721 BC072427 AAH72427 BU565530 CN354758 CR542239 CAG47035 HY043971 J03798 AAA36620 NM_001291916 NP_001278845 NM_006938 NP_008869
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. {ECO:0000269|PubMed:18984161, ECO:0000269|PubMed:23333303}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:18984161}. Nucleus {ECO:0000269|PubMed:18984161}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Top Pathways Systemic lupus erythematosus, Spliceosome

SNRPD1-Antibody-Center-Blocking-Peptide - BP2842c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SNRPD1-Antibody-C-term-Blocking-Peptide - BP2842b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Sm/RNP Antigen Protein (OPMA04153) - OPMA04153 from Aviva Systems Biology

Category Protein
Prices $490.00
Sizes 1,000 units
Source Rabbit and bovine thymus of US origin

Sm/RNP Antigen Protein (OPMA04228) - OPMA04228 from Aviva Systems Biology

Category Protein
Prices $255.00
Sizes 200 µg
Source Calf Thymus

Human SNRPD protein - orb169328 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Species Human

Bovine SNRPD protein - orb169569 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Source Bovine tissues.

SNRPD1 fusion protein - ag16331 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

SNRPD1 fusion protein - ag0364 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human SNRPD protein - BP002064-PRO-997 from Syd Labs

Category Protein
Prices $160.00, $5,200.00
Sizes 10 µg, 1 mg
Source Sf9 insect cells-derived.
Species Human

Recombinant Human SNRPD1 protein - BP002065-PRO-994 from Syd Labs

Category Protein
Prices $160.00, $5,200.00
Sizes 10 µg, 1 mg
Source Sf9 insect cells-derived.
Species Human

Sm/RNP Antigen - GWB-CDBE95 from Genway Biotech

Category Protein
Prices $589.00
Sizes 1000 units

Sm/RNP Antigen - GWB-CA4A65 from Genway Biotech

Category Protein
Prices $277.00
Sizes 200 µg

Recombinant Small Nuclear Ribonucleoprotein Polypeptide D1 (SNRPD1) - RPB128Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Small Nuclear Ribonucleoprotein Polypeptide D1 (SNRPD1) - RPB128Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Small nuclear ribonucleoprotein Sm D1(SNRPD1) - CSB-YP022332HU CSB-EP022332HU CSB-BP022332HU CSB-MP022332HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

SmD1 (83-119) - M07050 from Creative Peptides

Category Peptide

Smd1 - AF3175 from Creative Peptides

Category Peptide
Source Stomoxys calcitrans

Small nuclear ribonucleoprotein Sm D1 (11-19) - ta-236 from Creative Peptides

Category Peptide
Source Homo sapiens (human)

SNRPD1 Recombinant Protein (OPCD07088) - OPCD07088 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human

Small Nuclear Ribonucleoprotein, Recombinant Protein - MBS145171 from MyBioSource

Category Protein
Prices $140.00, $205.00, $5,015.00
Sizes 2 µg, 10 µg, 1 mg
Source Sf9 Insect Cells

Small nuclear ribonucleoprotein Sm D1 (SNRPD1), Recombinant Protein - MBS718933 from MyBioSource

Category Protein
Prices $855.00, $855.00, $1,080.00, $1,080.00, $1,235.00, $1,235.00, $1,695.00, $1,695.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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