Gene Symbol | POLR1E |
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Entrez Gene | 64425 |
Alt Symbol | PAF53, PRAF1 |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (RNA) I polypeptide E, 53kDa |
Other Description | DNA-directed RNA polymerase I subunit E|DNA-directed RNA polymerase I subunit RPA49|RNA polymerase I subunit A49|RNA polymerase I-associated factor 53|polymerase (RNA) I associated factor 1 |
Swissprots | Q5VZT3 Q96L20 Q8NBA9 Q9GZS1 |
Accessions | EAW58280 EAW58281 Q9GZS1 AK023452 BAB14579 AK024032 BAB14791 AK091294 BAC03629 AK125471 AK225050 AK301347 BAG62895 AK302345 BAG63673 AK303167 BAG64267 BC001337 AAH01337 BC009757 BC014180 BC014331 AAH14331 BC017766 CR457313 CAG33594 XM_005251547 XP_005251604 NM_001282766 NP_001269695 NM_022490 NP_071935 |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
Top Pathways | Purine metabolism, RNA polymerase, Pyrimidine metabolism |
Human PRAF1 full length protein - ab163839 from Abcam
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POLR1E Antibody Blocking Peptide - LS-E4726 from LifeSpan Bioscience
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POLR1E Antibody Blocking Peptide - LS-E21046 from LifeSpan Bioscience
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Recombinant Human PRAF1 Protein - H00064425-P01 from Novus Biologicals
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POLR1E-Antibody-Center-Blocking-Peptide - BP17099c from Abgent, a WuXi AppTec company
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POLR1E Blocking Peptide - 33R-8675 from Fitzgerald
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POLR1E - H00064425-P01 from Acris Antibodies
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POLR1E fusion protein - ag9579 from Proteintech Group
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POLR1E fusion protein - Ag9269 from Proteintech Group
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Recombinant Human POLR1E, GST-tagged - POLR1E-1840H from Creative Biomart
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Recombinant Human DNA-directed RNA polymerase I subunit RPA49(POLR1E) - CSB-YP887937HU CSB-EP887937HU CSB-BP887937HU CSB-MP887937HU from Cusabio
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POLR1E - TP304811 from Acris Antibodies
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PRAF1 Recombinant Protein Antigen - NBP1-89867PEP from Novus Biologicals
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POLR1E Peptide, Human - M34GP12088H from Creative Peptides
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PRAF1 Recombinant Protein Antigen - NBP2-56173PEP from Novus Biologicals
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DNA-directed RNA polymerase I subunit RPA49 (POLR1E), Recombinant Protein - MBS1380783 from MyBioSource
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