ZFYVE9

Gene Symbol	ZFYVE9
Entrez Gene	9372
Alt Symbol	MADHIP, NSP, PPP1R173, SARA, SMADIP
Species	Human
Gene Type	protein-coding
Description	zinc finger, FYVE domain containing 9
Other Description	MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor|MADH-interacting protein|novel serine protease|protein phosphatase 1, regulatory subunit 173|smad anchor for receptor activation|zinc finger FYVE domain-containing protein 9
Swissprots	Q5T0F7 Q9Y5R7 O95405 Q9UNE1 Q5T0F6
Accessions	CCQ43282 EAX06790 EAX06791 EAX06792 O95405 AB209125 BAD92362 AF104304 AAC99462 AF130419 AAD31694 AF130420 AAD31695 BC032680 AAH32680 DR005493 EU176568 ABW03369 XM_011542437 XP_011540739 NM_004799 NP_004790 NM_007324 NP_015563 NM_007323
Function	Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. {ECO:0000269|PubMed:15356634, ECO:0000269|PubMed:9865696}.
Subcellular Location	Cytoplasm. Early endosome membrane.
Tissue Specificity	Ubiquitous. In the brain found primarily in the cerebrovascular smooth muscle cells and reactive astrocytes.
Top Pathways	TGF-beta signaling pathway, Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SARA protein (His-DHFR tag) - ab127442 from Abcam Category Protein Source E. coli Species Human

RTN1 / Reticulon 1 Antibody Blocking Peptide - LS-E4802 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RTN1 / Reticulon 1 Antibody Blocking Peptide - LS-E17906 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RTN1 / Reticulon 1 Antibody Blocking Peptide - LS-E17907 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ZFYVE9 Protein - H00009372-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ZFYVE9 - H00009372-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

ZFYVE9 - H00009372-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZFYVE9 - H00009372-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZFYVE9 fusion protein - Ag16929 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ZFYVE9 fusion protein - ag14192 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ZFYVE9 fusion protein - Ag6592 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human ZFYVE9, His-tagged - ZFYVE9-3807H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Reticulon 4 (RTN4) - RPF994Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Zinc finger FYVE domain-containing protein 9(ZFYVE9) ,partial - CSB-YP026477HU CSB-EP026477HU CSB-BP026477HU CSB-MP026477HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SARA (1-300) - sc-4493 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

Zinc finger FYVE domain-containing protein 9(ZFYVE9) ,partial, Recombinant Protein - MBS1223405 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ZFYVE9 Peptide, Human - M34GP17820H from Creative Peptides Category Peptide Source Synthetic. Species Human

ZFYVE9 Recombinant Protein Antigen - NBP2-57583PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZFYVE9 Recombinant Protein Antigen - NBP2-57521PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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