ZFYVE9

Gene Symbol	ZFYVE9
Entrez Gene	9372
Alt Symbol	MADHIP, NSP, PPP1R173, SARA, SMADIP
Species	Human
Gene Type	protein-coding
Description	zinc finger, FYVE domain containing 9
Other Description	MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor|MADH-interacting protein|novel serine protease|protein phosphatase 1, regulatory subunit 173|smad anchor for receptor activation|zinc finger FYVE domain-containing protein 9
Swissprots	Q5T0F7 Q9Y5R7 O95405 Q9UNE1 Q5T0F6
Accessions	CCQ43282 EAX06790 EAX06791 EAX06792 O95405 AB209125 BAD92362 AF104304 AAC99462 AF130419 AAD31694 AF130420 AAD31695 BC032680 AAH32680 DR005493 EU176568 ABW03369 XM_011542437 XP_011540739 NM_004799 NP_004790 NM_007324 NP_015563 NM_007323
Function	Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. {ECO:0000269|PubMed:15356634, ECO:0000269|PubMed:9865696}.
Subcellular Location	Cytoplasm. Early endosome membrane.
Tissue Specificity	Ubiquitous. In the brain found primarily in the cerebrovascular smooth muscle cells and reactive astrocytes.
Top Pathways	TGF-beta signaling pathway, Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® Sara siRNA II - 13553 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® Sara siRNA I - 13542 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SARA CRISPR/Cas9 KO Plasmid (h) - sc-403648 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA HDR Plasmid (h) - sc-403648-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA Double Nickase Plasmid (h) - sc-403648-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA Double Nickase Plasmid (h2) - sc-403648-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA CRISPR Activation Plasmid (h) - sc-403648-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA CRISPR Activation Plasmid (h2) - sc-403648-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA Lentiviral Activation Particles (h) - sc-403648-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA Lentiviral Activation Particles (h2) - sc-403648-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

SARA siRNA (h) - sc-36458 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SARA shRNA Plasmid (h) - sc-36458-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SARA shRNA (h) Lentiviral Particles - sc-36458-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ZFYVE9 RNAi - H00009372-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ZFYVE9 RNAi - H00009372-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ZFYVE9 RNAi - H00009372-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU065421 from Sigma-Aldrich Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN23210 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23210 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ZFYVE9 siRNA (Human) - CRH6208 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ZFYVE9 - MBS8203571 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ZFYVE9 (NM_004799.2) - SHH452540 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ZFYVE9(NM_007324.2) - SHR205224 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ZFYVE9(NM_007323.1) - SHR205242 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ZFYVE9(NM_004799.2) - SHR205260 from Creative biogene Category siRNA Species Reactivities Human

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