CCL16

Gene Symbol	CCL16
Entrez Gene	6360
Alt Symbol	CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 16
Other Description	C-C motif chemokine 16|IL-10-inducible chemokine|chemokine LEC|liver CC chemokine-1|liver-expressed chemokine|lymphocyte and monocyte chemoattractant|monotactin-1|new CC chemokine 4|small inducible cytokine subfamily A (Cys-Cys), member 16|small-inducible cytokine A16
Swissprots	Q4KKU0 O15467
Accessions	AAC63330 AAC97450 BAA35138 EAW80114 O15467 AB007454 BAA24057 AF039955 AAC97451 AF055467 AAC28844 BC096352 BC099662 AAH99662 BC099663 BC099664 BQ722834 U91746 AAC05587 XM_005258020 XP_005258077 XM_006725334 XP_006725397 NM_004590 NP_004581
Function	Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Subcellular Location	Secreted.
Tissue Specificity	Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HCC-4 (L-15) - sc-33230 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

HCC-4 (N-12) - sc-33229 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

HCC-4 (N-14) - sc-12264 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Active human LEC full length protein - ab191719 from Abcam Prices $192.00 Sizes 25 µg

Anti-LEC antibody - ab626 from Abcam Prices $370.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-LEC antibody - ab113220 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LEC antibody - ab628 from Abcam Prices $370.00 Sizes 500 µg Host Mouse Clonality Monoclonal

Anti-LEC antibody (Biotin) - ab83141 from Abcam Host Goat Clonality Polyclonal

Anti-LEC antibody [EPR4451(2)] - ab126717 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR4451(2)

Anti-LEC antibody [EPR4452(2)] - ab134917 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR4452(2)

Anti-LEC antibody [LEC66] - ab190722 from Abcam Prices $370.00 Sizes 500 µl Host Mouse Clonality Monoclonal Clone LEC66

Anti-LEC antibody [MM0140-3J10] - ab89460 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone MM0140-3J10

Anti-LEC antibody - C-terminal - ab199162 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody - LS-C104839 from LifeSpan Bioscience Prices $255.00 Sizes 500 µg Host Mouse Clonality Monoclonal

Anti-CCL16 / LEC Antibody - LS-C104530 from LifeSpan Bioscience Prices $285.00, $325.00 Sizes 50 µg, 100 µg Host Goat Clonality Polyclonal

Anti-CCL16 / LEC Antibody - LS-C16192 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-CCL16 / LEC Antibody (C-Terminus) - LS-C112302 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (aa20-120, FITC) - LS-C301957 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (aa20-120, Biotin) - LS-C300891 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (HRP) - LS-C318223 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (FITC) - LS-C318224 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (Biotin) - LS-C318225 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (Biotin) - LS-C104529 from LifeSpan Bioscience Prices $285.00, $325.00 Sizes 25 µg, 50 µg Host Goat Clonality Polyclonal

Anti-CCL16 / LEC Antibody - LS-C319040 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-CCL16 / LEC Antibody (Internal, clone EPR4451(2)) - LS-C152371 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR4451(2)

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