CCL16

Gene Symbol	CCL16
Entrez Gene	6360
Alt Symbol	CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 16
Other Description	C-C motif chemokine 16|IL-10-inducible chemokine|chemokine LEC|liver CC chemokine-1|liver-expressed chemokine|lymphocyte and monocyte chemoattractant|monotactin-1|new CC chemokine 4|small inducible cytokine subfamily A (Cys-Cys), member 16|small-inducible cytokine A16
Swissprots	Q4KKU0 O15467
Accessions	AAC63330 AAC97450 BAA35138 EAW80114 O15467 AB007454 BAA24057 AF039955 AAC97451 AF055467 AAC28844 BC096352 BC099662 AAH99662 BC099663 BC099664 BQ722834 U91746 AAC05587 XM_005258020 XP_005258077 XM_006725334 XP_006725397 NM_004590 NP_004581
Function	Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Subcellular Location	Secreted.
Tissue Specificity	Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human LEC full length protein - ab194163 from Abcam Category Protein Prices $155.00 Sizes 10 µg Source Mammalian Species Human

Active human LEC full length protein - ab116400 from Abcam Category Protein Prices $192.00 Sizes 5 µg Source E. coli Species Human

Active LEC full length protein - ab627 from Abcam Category Protein Prices $110.00, $239.00 Sizes 5 µg, 20 µg Source E. coli

Human LEC full length protein - ab193752 from Abcam Category Protein Source Mammalian Species Human

CCL16 / LEC Antibody Blocking Peptide - LS-E10730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCL16 / LEC Antibody Blocking Peptide - LS-E25177 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CCL16/HCC-4/LEC Protein - NBP2-35138 from Novus Biologicals Category Protein Prices $69.00, $169.00, $2,669.00 Sizes 5 µg, 20 µg, 1 mg Source E. coli Species Human

CCL16/HCC-4/LEC Partial Recombinant Protein - H00006360-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCL16/HCC-4/LEC Recombinant Protein - P3620 from Novus Biologicals Category Protein Prices $369.00 Sizes 25 µg Species Human

Recombinant Human CCL16/HCC-4/LEC Protein - NBP1-99336 from Novus Biologicals Category Protein Prices $190.00 Sizes 20 µg Source E. coli Species Human

CCL16 Recombinant Protein (Active) - GTX48146-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source E. coli Species Human

Recombinant Human CCL16/HCC-4 - 802-HC-025 from R&D Systems Category Protein Source E. coli-derived, Gln24-Gln120

Recombinant Human CCL16/HCC-4, CF - 802-HC-025/CF from R&D Systems Category Protein Source E. coli-derived, Gln24-Gln120

CCL16 Protein (OPPA01592) - OPPA01592 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

CCL16 protein - orb197679 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Human LEC protein - orb82737 from Biorbyt Category Protein Prices $2,125.00 Sizes 1 mg Source E.coli

Human CCL16 protein - orb80119 from Biorbyt Category Protein Prices $264.00, $357.00, $629.00, $1,046.00, $1,751.00, $2,865.00 Sizes 5 μg, 20 μg, 100 μg, 250 μg, 500 μg, 1 mg Source E.coli Species Human

CCL16 (His Tag) protein - orb171566 from Biorbyt Category Protein Prices $298.00, $434.00 Sizes 20 μg, 50 μg Source E. coli Species Human

Human CCL16 protein - orb244076 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human CCL16 protein - orb49260 from Biorbyt Category Protein Prices $349.00, $536.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

CCL16 (His Tag) protein - orb171567 from Biorbyt Category Protein Prices $298.00, $434.00 Sizes 20 μg, 50 μg Source Yeast Species Human

NCC4 protein - orb108498 from Biorbyt Category Protein Prices $689.00 Sizes 20 μg

Human CCL16 protein - orb168049 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CCL16 Blocking Peptide - 33R-5134 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CCL16 Blocking Peptide - 33R-8609 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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