CCL16

Gene Symbol CCL16
Entrez Gene 6360
Alt Symbol CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) ligand 16
Other Description C-C motif chemokine 16|IL-10-inducible chemokine|chemokine LEC|liver CC chemokine-1|liver-expressed chemokine|lymphocyte and monocyte chemoattractant|monotactin-1|new CC chemokine 4|small inducible cytokine subfamily A (Cys-Cys), member 16|small-inducible cytokine A16
Swissprots Q4KKU0 O15467
Accessions AAC63330 AAC97450 BAA35138 EAW80114 O15467 AB007454 BAA24057 AF039955 AAC97451 AF055467 AAC28844 BC096352 BC099662 AAH99662 BC099663 BC099664 BQ722834 U91746 AAC05587 XM_005258020 XP_005258077 XM_006725334 XP_006725397 NM_004590 NP_004581
Function Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Subcellular Location Secreted.
Tissue Specificity Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma- activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

HCC-4 CRISPR/Cas9 KO Plasmid (h) - sc-411002 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 HDR Plasmid (h) - sc-411002-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 Double Nickase Plasmid (h) - sc-411002-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 Double Nickase Plasmid (h2) - sc-411002-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 CRISPR Activation Plasmid (h) - sc-411002-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 CRISPR Activation Plasmid (h2) - sc-411002-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 Lentiviral Activation Particles (h) - sc-411002-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 Lentiviral Activation Particles (h2) - sc-411002-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCC-4 siRNA (h) - sc-39353 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCC-4 shRNA Plasmid (h) - sc-39353-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCC-4 shRNA (h) Lentiviral Particles - sc-39353-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN5601 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5601 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07775 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07775

CCL16 siRNA (Human) - CRH4293 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCL16 - MBS8200447 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CCL16 (NM_004590.2) - SHH257517 from Creative biogene

Category siRNA
Species Reactivities Human

CCL16 shRNA Plasmid (Human) - CHH4293 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCL16 miRNA 3'UTR clone - MiUTR1H-01792 from Creative biogene

Species Reactivities Human
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