Htr1b

Gene Symbol Htr1b
Entrez Gene 15551
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 1B
Other Description 5-HT-1B|5-HT1B receptor|5-HT<1B> receptor|5-hydroxytryptamine receptor 1B|serotonin receptor 1B
Swissprots P28334
Accessions AAA83221 CAA77678 EDL26441 P28334 BC119129 AAI19130 BC131951 AAI31952 NM_010482 NP_034612
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries. {ECO:0000269|PubMed:10651141, ECO:0000269|PubMed:1557407, ECO:0000269|PubMed:16750486, ECO:0000269|PubMed:8091214, ECO:0000269|PubMed:8742487, ECO:0000269|PubMed:9349547}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:1557407}; Multi-pass membrane protein {ECO:0000269|PubMed:1557407}.
Tissue Specificity Predominantly expressed in striatum and Purkinje cells. {ECO:0000269|PubMed:1557407}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

5-hydroxytryptamine receptor 1B, Htr1b, Mouse, ELISA Kit - E10279m from ARP American Research Products

Category ELISA Kit
Prices $736.00
Sizes 96 t

5-hydroxytryptamine (serotonin) receptor 1B, ELISA Kit - MBS9325477 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Htr1b ELISA Kit - E073762 from Biobool

Category ELISA Kit

HTR1B ELISA Kit (Mouse) (OKEH05737) - OKEH05737 from Aviva Systems Biology

Category ELISA Kit
Prices $500.00
Sizes 96 wells
Sensitivity 0.16 ng/mL
Range 0.312-20 ng/mL

5-hydroxytryptamine receptor 1B, ELISA Kit - MBS289883 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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