SGK2

Gene Symbol SGK2
Entrez Gene 10110
Alt Symbol H-SGK2, dJ138B7.2
Species Human
Gene Type protein-coding
Description serum/glucocorticoid regulated kinase 2
Other Description serine/threonine-protein kinase Sgk2
Swissprots Q52PK5 Q5H8Z1 Q9UKG6 Q9HBY8 Q5TZR3 Q5H8Y6
Accessions EAW75955 EAW75956 Q9HBY8 AF169034 AAF12757 AF186470 AAG17012 AK289596 BAF82285 AK308502 AY987010 AAX88805 BC006523 BC014037 AAH14037 BC065511 AAH65511 BG420383 BT020098 AAV38901 CD627734 DA244897 DB183229 DC385330 NM_001199264 NP_001186193 NM_016276 NP_057360 NM_170693 NP_733794
Function Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. {ECO:0000269|PubMed:12397388, ECO:0000269|PubMed:12590200, ECO:0000269|PubMed:12632189, ECO:0000269|PubMed:12634932, ECO:0000269|PubMed:15040001, ECO:0000269|PubMed:20511718, ECO:0000269|PubMed:21865597}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21865597}. Nucleus {ECO:0000269|PubMed:21865597}.
Tissue Specificity Highly expressed in liver, kidney and pancreas, and at lower levels in brain. {ECO:0000269|PubMed:10548550}.
Top Pathways PI3K-Akt signaling pathway

SGK2 Antibody - 5595 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from human and mouse liver tissues using SGK2 Antibody.

SGK2 (D7G1) Rabbit mAb - 7499 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7G1
Western blot analysis of extracts from HT-29 cells, mouse liver, and rat liver using SGK2 (D7G1) Rabbit mAb.

SGK2 (N-14) - sc-47392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SGK2 (N-14): sc-47392. Western blot analysis of SGK2 expression in non-transfected 293T: sc-117752 (A), human SGK2 transfected 293T: sc-116881 (B) and PC-12 (C) whole cell lysates.

SGK2 (H-45) - sc-98972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SGK2 (G-13) - sc-47391 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SGK2 (D-13) - sc-47390 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SGK2 (3Q-2) - sc-100355 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SGK2 (3Q-2): sc-100355. Western blot analysis of SGK2 expression in PC-12 whole cell lysate.

Anti-SGK2 antibody - ab89144 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-SGK2 antibody (ab89144) at 5 µg/ml + tagged, recombinant human SGK2 protein (the immunogen) at 0.2 µg

Anti-SGK2 antibody - ab56826 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SGK2 antibody - ab172557 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SGK2 antibody (ab172557) at 1 µg/mlLane 1 : SGK2 transfected 293T cell line lysateLane 2 : 293T cell line lysate (non-transfected)Lysates/proteins at 15 µl per lane.SecondaryGoat anti-mouse HRP conjugated antibody at 1/2500 dilutiondeveloped using the ECL technique

Anti-SGK2 antibody - Carboxyterminal end - ab71616 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SGK2 antibody - Carboxyterminal end (ab71616) at 1/100 dilution + placenta lysate at 12.5 µgSecondaryHRP anti rabbit

Anti-SGK2 antibody - N-terminal - ab189293 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue, labeling SGK2 using ab189293 at 1 µg/ml.

Anti-SGK2 Antibody (Internal) IHC-plus™ - LS-A7221 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SGK2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SGK2 Antibody (Kinase Domain) IHC-plus™ - LS-A7220 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SGK2 antibody LS-A7220 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-SGK2 Antibody - LS-C132060 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus, AP) - LS-C226333 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus, APC) - LS-C226334 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus, Biotin) - LS-C226335 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus, FITC) - LS-C226336 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus, Azide-free, HRP) - LS-C226337 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus, PE) - LS-C226338 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (C-Terminus) - LS-C328638 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGK2 Antibody (clone 1G11) - LS-C133625 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G11
Immunoperoxidase of monoclonal antibody to SGK2 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]

Anti-SGK2 Antibody (aa395-426) - LS-C99744 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-SGK2 Antibody (N-Terminus) IHC-plus™ - LS-A7218 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SGK2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A7218 dilution 1 ug/ml.
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