SGK2

Gene Symbol SGK2
Entrez Gene 10110
Alt Symbol H-SGK2, dJ138B7.2
Species Human
Gene Type protein-coding
Description serum/glucocorticoid regulated kinase 2
Other Description serine/threonine-protein kinase Sgk2
Swissprots Q52PK5 Q5H8Z1 Q9UKG6 Q9HBY8 Q5TZR3 Q5H8Y6
Accessions EAW75955 EAW75956 Q9HBY8 AF169034 AAF12757 AF186470 AAG17012 AK289596 BAF82285 AK308502 AY987010 AAX88805 BC006523 BC014037 AAH14037 BC065511 AAH65511 BG420383 BT020098 AAV38901 CD627734 DA244897 DB183229 DC385330 NM_001199264 NP_001186193 NM_016276 NP_057360 NM_170693 NP_733794
Function Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. {ECO:0000269|PubMed:12397388, ECO:0000269|PubMed:12590200, ECO:0000269|PubMed:12632189, ECO:0000269|PubMed:12634932, ECO:0000269|PubMed:15040001, ECO:0000269|PubMed:20511718, ECO:0000269|PubMed:21865597}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21865597}. Nucleus {ECO:0000269|PubMed:21865597}.
Tissue Specificity Highly expressed in liver, kidney and pancreas, and at lower levels in brain. {ECO:0000269|PubMed:10548550}.
Top Pathways PI3K-Akt signaling pathway

SGK2 CRISPR/Cas9 KO Plasmid (h) - sc-410557 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 HDR Plasmid (h) - sc-410557-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 Double Nickase Plasmid (h) - sc-410557-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 Double Nickase Plasmid (h2) - sc-410557-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 CRISPR Activation Plasmid (h) - sc-410557-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 CRISPR Activation Plasmid (h2) - sc-410557-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 Lentiviral Activation Particles (h) - sc-410557-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 Lentiviral Activation Particles (h2) - sc-410557-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SGK2 siRNA (h) - sc-61536 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SGK2 shRNA Plasmid (h) - sc-61536-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SGK2 shRNA (h) Lentiviral Particles - sc-61536-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SGK2 RNAi - H00010110-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SGK2 RNAi - H00010110-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU069281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK2062 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2063 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2061 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN19227 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19227 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05364 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05364

SGK2 siRNA (Human) - CRH6816 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SGK2 - MBS826938 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SGK2 (NM_016276.3) - SHH406268 from Creative biogene

Category siRNA
Species Reactivities Human

Human SGK2 siRNA - orb267318 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SGK2 shRNA Plasmid (Human) - CHH6816 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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