SGK2

Gene Symbol	SGK2
Entrez Gene	10110
Alt Symbol	H-SGK2, dJ138B7.2
Species	Human
Gene Type	protein-coding
Description	serum/glucocorticoid regulated kinase 2
Other Description	serine/threonine-protein kinase Sgk2
Swissprots	Q52PK5 Q5H8Z1 Q9UKG6 Q9HBY8 Q5TZR3 Q5H8Y6
Accessions	EAW75955 EAW75956 Q9HBY8 AF169034 AAF12757 AF186470 AAG17012 AK289596 BAF82285 AK308502 AY987010 AAX88805 BC006523 BC014037 AAH14037 BC065511 AAH65511 BG420383 BT020098 AAV38901 CD627734 DA244897 DB183229 DC385330 NM_001199264 NP_001186193 NM_016276 NP_057360 NM_170693 NP_733794
Function	Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. {ECO:0000269|PubMed:12397388, ECO:0000269|PubMed:12590200, ECO:0000269|PubMed:12632189, ECO:0000269|PubMed:12634932, ECO:0000269|PubMed:15040001, ECO:0000269|PubMed:20511718, ECO:0000269|PubMed:21865597}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21865597}. Nucleus {ECO:0000269|PubMed:21865597}.
Tissue Specificity	Highly expressed in liver, kidney and pancreas, and at lower levels in brain. {ECO:0000269|PubMed:10548550}.
Top Pathways	PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human SGK2 full length protein - ab56283 from Abcam Category Protein Prices $192.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Human SGK2 full length protein - ab160823 from Abcam Category Protein Source Wheat germ Species Human

Human SGK2 protein fragment - ab160824 from Abcam Category Protein Source Wheat germ Species Human

SGK2 Antibody Blocking Peptide - LS-E9386 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SGK2 Antibody Blocking Peptide - LS-E29242 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SGK2 Antibody Blocking Peptide - LS-E29241 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SGK2 Antibody Blocking Peptide - LS-E29243 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human SGK2 Protein - H00010110-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SGK2 Protein - H00010110-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SGK2 Recombinant Protein - P4232 from Novus Biologicals Category Protein Prices $549.00 Sizes 5 µg Species Human

Recombinant SGK2 Protein - NBP1-99490 from Novus Biologicals Category Protein Prices $295.00 Sizes 5 µg Source Baculovirus (Sf9 insect cells)

SGK2 Peptide - P2935 from Novus Biologicals Category Peptide Species Human

SGK2-Antibody-C-term-Blocking-Peptide - BP7947b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SGK2 (Active) recombinant protein - GTX65310 from GeneTex Category Protein Prices $329.00 Sizes 5 μg Source Baculovirus (Sf9 insect cells) Species Human

SGK2 protein - 30R-2863 from Fitzgerald Category Protein Prices $250.00 Sizes 5 µg Source Sf-9 insect cells Species Human

SGK2 - H00010110-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SGK2 - H00010110-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SGK2 - H00010110-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SGK2 - H00010110-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SGK2 - P4232 from Acris Antibodies Category Protein Prices $670.00 Sizes 5 µg Species Human

SGK2 - P5749 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

SGK2 fusion protein - ag1669 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SGK2, GST-tagged, Active - SGK2-429H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

Recombinant Human Serum/Glucocorticoid Regulated Kinase 2 - SGK2-659H from Creative Biomart Category Protein Source E.coli.

Recombinant Human SGK2, GST-tagged - SGK2-2631H from Creative Biomart Category Protein Source E.coli Species Human

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