RNF125

Gene Symbol RNF125
Entrez Gene 54941
Alt Symbol TNORS, TRAC-1, TRAC1
Species Human
Gene Type protein-coding
Description ring finger protein 125, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase RNF125|T-cell RING activation protein 1|T-cell ring protein identified in activation screen
Swissprots Q96EQ8 Q9NX39
Accessions EAX01278 Q96EQ8 AK000463 BAA91182 AK027134 AK225518 BC012021 AAH12021 BI666910 BM469263 BU500546 XM_011526045 XP_011524347 XM_011526046 XP_011524348 XM_011526047 XP_011524349 NM_017831 NP_060301
Function E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:15843525}.
Tissue Specificity Predominantly expressed in lymphoid tissues, including bone marrow, spleen and thymus. Also weakly expressed in other tissues. Predominant in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells. {ECO:0000269|PubMed:12974981, ECO:0000269|PubMed:15843525}.
Top Pathways RIG-I-like receptor signaling pathway

TRAC-1 (C-17) - sc-85188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRAC-1 (C-17): sc-85188. Western blot analysis of TRAC-1 expression in HT-29 whole cell lysate.

Anti-RNF125 antibody - ab74373 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RNF125 antibody (ab74373) at 1/200 dilutionLane 1 : 293T whole cell lysateLane 2 : Mouse ES (129Sv) whole cell lysateLysates/proteins at 5 µg per lane.SecondaryHRP-conjugated Donkey anti-rabbit IgG polyclonal at 1/5000 dilutionPerformed under reducing conditions.

Anti-RNF125 antibody - ab38315 from Abcam

Prices $242.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RNF125 / TRAC-1 Antibody (aa220-232) - LS-C55610 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RNF125 / TRAC-1 Antibody (aa100-150) - LS-C191350 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF125 / TRAC-1 Antibody (C-Terminus) - LS-C116230 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RNF125 antibody LS-C116230 Western blot of THP-1 cell lysate.

Anti-RNF125 Antibody IHC-plus™ - LS-B2822 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-RNF125 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2822 dilution 1:100.

Anti-RNF125 / TRAC-1 Antibody (aa131-180) IHC-plus™ - LS-B11326 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RNF125 antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

RNF125 Antibody - NBP2-23660 from Novus Biologicals

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RNF125 Antibody [NBP2-23660] - analysis of TRAC-1 in spleen lysate. Lane 1 shows pre-immune sera and lane 2 shows this antibody.

RNF125 Antibody - NBP1-55373 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

RNF125 Antibody - NBP1-83653 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RNF125 Antibody (1A5) - H00054941-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A5
Sandwich ELISA: RNF125 Antibody (1A5) [H00054941-M01] - Detection limit for recombinant GST tagged RNF125 is approximately 0.03ng/ml as a capture antibody.

RNF125 Antibody (1D3) - H00054941-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D3
Immunocytochemistry/Immunofluorescence: RNF125 Antibody (1D3) [H00054941-M03] - Analysis of monoclonal antibody to RNF125 on HeLa cell. Antibody concentration 10 ug/ml

Monoclonal Anti-RNF125, (C-terminal) antibody produced in mouse - SAB1405136 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D3
<B>Immunofluorescence</B><BR/>Monoclonal Anti-RNF125: <B>Cat. No. SAB1405136</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-RNF125 antibody produced in rabbit - SAB4502277 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RNF125: <B>Cat. No. SAB4502277</B>: Immunoblotting analysis of extracts from K562/HT-29 cells, using Anti-RNF125 antibody. The lane on the left was treated with the Anti-RNF125 antibody. The lane on the right (negative control) was treated with both Anti-RNF125 antibody and the synthesized immunogen peptide.

Monoclonal Anti-RNF125 antibody produced in mouse - WH0054941M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A5
<B>Immunoblotting</B><BR/>Monoclonal Anti-RNF125, <B>Cat. No. WH0054941M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~35.9 kDa using immunogen protein lysate.

Anti-RNF125 antibody produced in rabbit - HPA041514 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RNF125: <B>Cat. No. HPA041514</B>: Immunohistochemical staining of human pancreas shows moderate cytoplasmic and nuclear positivity in exocrine pancreas.

Anti-RNF125 antibody produced in rabbit - SAB2105504 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RNF125: <B>Cat. No. SAB2105504</B>: RNF125 in THP-1 cell lysates with RNF125 antibody at 1.0 μg/mL.

RNF125 antibody - middle region (ARP43234_P050) - ARP43234_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RNF125-Antibody-monoclonal-M01 - AT3661a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A5
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .

TRAC-1--RNF125-Antibody-C-Term - AF2412a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

RNF125 Antibody (OAAF03618) - OAAF03618 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Goat Anti-TRAC-1 / RNF125 Antibody (OAEB00776) - OAEB00776 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

RNF125 Antibody (OALA02907) - OALA02907 from Aviva Systems Biology

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RNF125 antibody - 70R-19919 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
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