RNF125

Gene Symbol	RNF125
Entrez Gene	54941
Alt Symbol	TNORS, TRAC-1, TRAC1
Species	Human
Gene Type	protein-coding
Description	ring finger protein 125, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase RNF125|T-cell RING activation protein 1|T-cell ring protein identified in activation screen
Swissprots	Q96EQ8 Q9NX39
Accessions	EAX01278 Q96EQ8 AK000463 BAA91182 AK027134 AK225518 BC012021 AAH12021 BI666910 BM469263 BU500546 XM_011526045 XP_011524347 XM_011526046 XP_011524348 XM_011526047 XP_011524349 NM_017831 NP_060301
Function	E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:15843525}.
Tissue Specificity	Predominantly expressed in lymphoid tissues, including bone marrow, spleen and thymus. Also weakly expressed in other tissues. Predominant in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells. {ECO:0000269|PubMed:12974981, ECO:0000269|PubMed:15843525}.
Top Pathways	RIG-I-like receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RNF125 protein fragment - ab162904 from Abcam Category Protein Source Wheat germ Species Human

RNF125 / TRAC-1 Antibody Blocking Peptide - LS-E25728 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RNF125 Protein - H00054941-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RNF125 blocking peptide - GTX89730-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Rat, Bovine

RNF125 Blocking Peptide - 33R-2614 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RNF125 Peptide - AC21-0557-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

RNF125 - H00054941-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RNF125 - H00054941-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RNF125 Peptide - 46-303P from ProSci Category Peptide

RNF125 fusion protein - ag3908 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human E3 ubiquitin-protein ligase RNF125(RNF125) - CSB-YP836205HU CSB-EP836205HU CSB-BP836205HU CSB-MP836205HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RNF125 Blocking Peptide - CBP4205 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Monkey

RNF125 Blocking Peptide - abx161416 from Abbexa Category Peptide Species Human, Mouse, Monkey

RNF125 Protein - abx163650 from Abbexa Category Protein Species Human

TRAC-1/RNF125, Peptide - MBS425998 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

RNF125 Recombinant Protein Antigen - NBP1-83653PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RNF125 Peptide, Human - M34GP13377H from Creative Peptides Category Peptide Source Synthetic. Species Human

RNF125 fusion protein - Ag26719 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Human RNF125 protein - orb54304 from Biorbyt Category Protein Prices $289.00, $408.00, $476.00, $765.00, $1,275.00, $2,023.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

E3 ubiquitin-protein ligase RNF125 (RNF125), Recombinant Protein - MBS1279917 from MyBioSource Category Protein Prices $985.00, $985.00, $1,210.00, $1,210.00, $1,485.00, $1,485.00, $1,950.00, $1,950.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

RNF125 Recombinant Protein (Human) (OPCA04791) - OPCA04791 from Aviva Systems Biology Category Protein Species Human

Recombinant Human RNF125 Protein (1-232 aa), GST-tagged - RNF125-2119H from Creative Biomart Category Protein Source E. coli Species Human

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