Gene Symbol | AKTIP |
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Entrez Gene | 64400 |
Alt Symbol | FT1, FTS |
Species | Human |
Gene Type | protein-coding |
Description | AKT interacting protein |
Other Description | AKT-interacting protein|fused toes homolog|fused toes protein homolog |
Swissprots | Q53H38 Q9H8T0 Q503B1 |
Accessions | CAD10180 EAW82803 EAW82804 EAW82805 EAW82806 EAW82807 EAW82808 EAW82809 Q9H8T0 AK023320 BAB14524 AK098222 AK222743 BAD96463 AK303503 BAG64536 AL133106 CAH56392 BC001134 AAH01134 BC095401 AAH95401 BG568989 BI545474 BM992149 CR457308 CAG33589 HQ448037 ADQ32518 XM_005256094 XP_005256151 XM_005256095 XP_005256152 XM_005256096 XP_005256153 XM_005256097 XP_005256154 XM_005256098 XP_005256155 NM_001012398 NP_001012398 NM_001308325 NP_001295254 NM_022476 NP_071921 |
Function | Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. {ECO:0000269|PubMed:14749367, ECO:0000269|PubMed:18799622}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14749367}. Cell membrane {ECO:0000269|PubMed:14749367}; Peripheral membrane protein {ECO:0000269|PubMed:14749367}. |
Human FTS full length protein - ab163832 from Abcam
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AKTIP / FTS Antibody Blocking Peptide - LS-E20361 from LifeSpan Bioscience
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AKTIP / FTS Antibody Blocking Peptide - LS-E6590 from LifeSpan Bioscience
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Recombinant Human FTS Protein - H00064400-P01 from Novus Biologicals
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AKTIP-AntibodyC-term-Blocking-peptide - BP19369b from Abgent, a WuXi AppTec company
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Human AKTIP protein - orb244942 from Biorbyt
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AKTIP Blocking Peptide - 33R-6833 from Fitzgerald
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AKTIP / FTS - H00064400-P01-10 from Acris Antibodies
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AKTIP / FTS - H00064400-P01-25 from Acris Antibodies
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AKTIP fusion protein - Ag6787 from Proteintech Group
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AKTIP fusion protein - ag6662 from Proteintech Group
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Recombinant Human AKTIP, His-tagged - AKTIP-9543H from Creative Biomart
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Recombinant Human AKT-interacting protein(AKTIP) - CSB-YP862043HU CSB-BP862043HU CSB-MP862043HU from Cusabio
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Recombinant human AKT-interacting protein - CSB-EP862043HU from Cusabio
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AKT-interacting protein (AKTIP) - MBS1422053 from MyBioSource
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AKTIP / FTS (transcript variant 2) - TP315277 from Acris Antibodies
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FTS Recombinant Protein Antigen - NBP2-14278PEP from Novus Biologicals
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FTS Protein - NBP2-14279PEP from Novus Biologicals
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AKTIP Peptide, Human - M34GP00468H from Creative Peptides
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AKTIP Recombinant Protein (OPCA02458) - OPCA02458 from Aviva Systems Biology
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Recombinant human AKT-interacting protein - AP71516 from Signalway Antibody
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