Gene Symbol | VTN |
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Entrez Gene | 7448 |
Alt Symbol | V75, VN, VNT |
Species | Human |
Gene Type | protein-coding |
Description | vitronectin |
Other Description | S-protein|complement S-protein|epibolin|serum spreading factor|serum-spreading factor|somatomedin B |
Swissprots | Q9BSH7 B2R7G0 P04004 P01141 |
Accessions | AAK60270 ADL14521 AFQ00545 CAA28659 EAW51082 P04004 AI352496 AK298441 BAH12789 AK312968 BAG35807 BC005046 AAH05046 BG470977 BI758517 DQ893394 ABM84320 DQ896716 ABM87715 X03168 CAA26933 NM_000638 NP_000629 |
Function | Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Plasma. |
Top Pathways | Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, Proteoglycans in cancer |
Vitronectin 10/65/75 (H-202) - sc-28929 from Santa Cruz Biotechnology
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Vitronectin 10/75 (C-20) - sc-7776 from Santa Cruz Biotechnology
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Vitronectin 10/75 (D-18) - sc-30979 from Santa Cruz Biotechnology
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Vitronectin 65/75 (15) - sc-293081 from Santa Cruz Biotechnology
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Vitronectin 65/75 (B-1) - sc-74485 from Santa Cruz Biotechnology
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Vitronectin 65/75 (C-20) - sc-7777 from Santa Cruz Biotechnology
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Vitronectin 65/75 (D-8) - sc-74484 from Santa Cruz Biotechnology
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Vitronectin 65/75 (H-270) - sc-15332 from Santa Cruz Biotechnology
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Vitronectin 65/75 (N-20) - sc-30977 from Santa Cruz Biotechnology
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Vitronectin 75 (1D144) - sc-81694 from Santa Cruz Biotechnology
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Vitronectin 75 (GMA-900) - sc-65972 from Santa Cruz Biotechnology
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Vitronectin 75 (HVN1D144) - sc-81696 from Santa Cruz Biotechnology
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Vitronectin 75 (VN58-1) - sc-59807 from Santa Cruz Biotechnology
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Vitronectin 75 (HVN1E934) - sc-81697 from Santa Cruz Biotechnology
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Vitronectin 75 (1E934) - sc-81695 from Santa Cruz Biotechnology
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Anti-Vitronectin antibody - ab113700 from Abcam
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Anti-Vitronectin antibody - ab82379 from Abcam
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Anti-Vitronectin antibody - ab20091 from Abcam
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Anti-Vitronectin antibody - ab135913 from Abcam
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Anti-Vitronectin antibody [1G11E8] - ab201981 from Abcam
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Anti-Vitronectin antibody [BV1] - ab7165 from Abcam
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Anti-Vitronectin antibody [EP781Y] - ab46808 from Abcam
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Anti-Vitronectin antibody [EP873Y] - ab45139 from Abcam
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Anti-Vitronectin antibody [EP873Y] (HRP) - ab199310 from Abcam
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Anti-Vitronectin antibody [VIT-2] - ab11591 from Abcam
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