Gene Symbol | VTN |
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Entrez Gene | 7448 |
Alt Symbol | V75, VN, VNT |
Species | Human |
Gene Type | protein-coding |
Description | vitronectin |
Other Description | S-protein|complement S-protein|epibolin|serum spreading factor|serum-spreading factor|somatomedin B |
Swissprots | Q9BSH7 B2R7G0 P04004 P01141 |
Accessions | AAK60270 ADL14521 AFQ00545 CAA28659 EAW51082 P04004 AI352496 AK298441 BAH12789 AK312968 BAG35807 BC005046 AAH05046 BG470977 BI758517 DQ893394 ABM84320 DQ896716 ABM87715 X03168 CAA26933 NM_000638 NP_000629 |
Function | Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. |
Subcellular Location | Secreted, extracellular space. |
Tissue Specificity | Plasma. |
Top Pathways | Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, Proteoglycans in cancer |
VTN-Over-expression-Lysate - LY11542a from Abgent, a WuXi AppTec company
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VTN 293T Cell Transient Overexpression Lysate(Denatured) - H00007448-T01 from Acris Antibodies
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VTN 293 Cell Lysate - 400279 from ABBIOTEC
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Vitronectin Overexpression Lysate (Native) - NBL1-17770 from Novus Biologicals
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Vitronectin (h2): 293T Lysate - sc-170448 from Santa Cruz Biotechnology
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VTN Over-expression Lysate Product - GWB-B0F000 from Genway Biotech
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Human VTN / Vitronectin HEK293 Cell Lysate (WB positive control) - 10424-H08HL-300 from Sino Biological
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Vitronectin Overexpression Lysate (Denatured) - H00007448-T01 from Novus Biologicals
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Human VTN Human Cells Transfected Lysate (positive control) (denatured) - orb232824 from Biorbyt
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Panoply™ Human VTN Knockdown Stable Cell Line - CSC-DC017356 from Creative biogene
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