MGLL

Gene Symbol	MGLL
Entrez Gene	11343
Alt Symbol	HU-K5, HUK5, MAGL, MGL
Species	Human
Gene Type	protein-coding
Description	monoglyceride lipase
Other Description	lysophospholipase homolog|monoacylglycerol lipase
Swissprots	Q96AA5 B7Z9D1 B3KRC2 Q6IBG9 Q99685
Accessions	CBG21711 CBG21792 CBV34969 CBV35050 EAW79329 EAW79330 EAW79331 Q99685 AF131821 AI125141 AI379999 AJ270950 CAC43316 AK025983 AK026389 AK091314 BAG52334 AK093841 AK125135 AK304844 BAH14267 AK310874 AK315529 BAG37910 AL365376 AL833254 AW166623 AY172950 AAO45694 BC000551 AAH00551 BC006230 AAH06230 BC047298 BC073823 BE302457 BG035493 BG249567 BM051374 BM669411 BP307995 BX403703 BX640777 CAE45873 CR456835 CAG33116 DA240965 DQ891955 ABM82881 DQ895141 ABM86067 EU660904 ACD37712 U67963 AAB39616 XM_011512377 XP_011510679 XM_011512378 XP_011510680 XM_011512379 XP_011510681 XM_011512380 XP_011510682 XM_011512381 XP_011510683 XM_011512382 XP_011510684 XM_011512383 XP_011510685 NM_001003794 NP_001003794 NM_001256585 NP_001243514 NM_007283 NP_009214
Function	Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333). {ECO:0000250|UniProtKB:O35678, ECO:0000269|PubMed:20079333}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678}.
Tissue Specificity	Detected in adipose tissue, lung, liver, kidney, brain and heart. {ECO:0000269|PubMed:11470505}.
Top Pathways	Retrograde endocannabinoid signaling, Glycerolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Monoacylglycerol Lipase full length protein - ab198470 from Abcam Category Protein Prices $911.00 Sizes 100 µg Source Baculovirus infected sf9 cells Species Human

Human Monoacylglycerol Lipase full length protein - ab101045 from Abcam Category Protein Source E. coli Species Human

Monoacylglycerol Lipase peptide - ab173372 from Abcam Category Peptide

Monoacylglycerol Lipase peptide - ab82022 from Abcam Category Peptide

MGLL / Monoacylglycerol Lipase Antibody Blocking Peptide - LS-E4536 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MGLL / Monoacylglycerol Lipase Antibody Blocking Peptide - LS-E18813 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MGLL / Monoacylglycerol Lipase Antibody Blocking Peptide - LS-E26841 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Monoglyceride Lipase Recombinant Protein - H00011343-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Monoglyceride Lipase Protein - NBP1-50853 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E.coli Species Human

MGLL-Antibody-N-term-Blocking-Peptide - BP16876a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Monoglyceride lipase blocking peptide - GTX88653-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Recombinant Human Monoglyceride Lipase, CF - 7930-MG-010 from R&D Systems Category Protein Source E. coli-derived, Pro2-Pro303, with an N-terminal Met and 6-His tag

MGLL Protein (OPPA02551) - OPPA02551 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human MGLL protein - orb168816 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

MGLL Blocking Peptide - 33R-5968 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MGLL protein (His tag) - 80R-1528 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

Monoacylglycerol Lipase Peptide - AC21-1673-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Monoglyceride lipase (1-313, His-tag) - AR09706PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

Monoglyceride lipase (1-313, His-tag) - AR09706PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

Monoglyceride lipase - H00011343-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Monoglyceride lipase - H00011343-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Monoglyceride Lipase, Human Recombinant - 228-12175-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Monoglyceride Lipase Human - 228-12175-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Monoglyceride Lipase Human - 228-12175-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

MGLL, 1-313aa, Human, His tag, E.coli - 01-MGL-L from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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