Gene Symbol | HIP1R |
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Entrez Gene | 9026 |
Alt Symbol | HIP12, HIP3, ILWEQ |
Species | Human |
Gene Type | protein-coding |
Description | huntingtin interacting protein 1 related |
Other Description | HIP-12|HIP1-related protein|huntingtin interacting protein 12|huntingtin-interacting protein 1-related protein|huntingtin-interacting protein 12 |
Swissprots | A6NHQ6 Q9UED9 O75146 Q6NXG8 |
Accessions | EAW98346 EAW98347 O75146 AB013384 BAA33713 AB014555 BAA31630 AK024062 BAG51260 AK090537 BAG52180 AK295389 BAG58343 AK298387 BAG60622 AK307446 AK308538 AW962010 BC011354 BC038981 BC067085 AAH67085 CF454957 DA779723 DN999807 HY123489 XM_011538963 XP_011537265 XM_011538964 XP_011537266 NM_001303097 NP_001290026 NM_001303099 NP_001290028 NM_003959 NP_003950 |
Function | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. {ECO:0000269|PubMed:11889126, ECO:0000269|PubMed:14732715}. |
Subcellular Location | Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Note=Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region. |
Tissue Specificity | Brain, heart, kidney, pancreas, and liver, but not in lung or placenta. |
Hip1r (44) - sc-135937 from Santa Cruz Biotechnology
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HIP12 (H-300) - sc-366857 from Santa Cruz Biotechnology
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HIP12 (D-6) - sc-390803 from Santa Cruz Biotechnology
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HIP12 (1C5) - sc-58533 from Santa Cruz Biotechnology
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Anti-HIP1R antibody - ab77297 from Abcam
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Anti-HIP1R antibody - ab88468 from Abcam
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Anti-HIP1R antibody - ab79162 from Abcam
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Anti-HIP1R antibody [1C5] - ab5404 from Abcam
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Anti-HIP1R antibody [EPR9437] - ab140608 from Abcam
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Anti-HIP1R Antibody (aa98-126, APC) - LS-C215072 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa98-126, AP) - LS-C215073 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa98-126, Biotin) - LS-C215074 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa98-126, FITC) - LS-C215075 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa98-126, Azide-free, HRP) - LS-C215076 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa969-1067) - LS-C308240 from LifeSpan Bioscience
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Anti-HIP1R Antibody - LS-C310608 from LifeSpan Bioscience
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Anti-HIP1R Antibody - LS-C308239 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa98-126, PE) - LS-C215077 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa105-133) - LS-C321955 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa98-126) - LS-C166875 from LifeSpan Bioscience
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Anti-HIP1R Antibody (N-Terminus) - LS-C155473 from LifeSpan Bioscience
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Anti-HIP1R Antibody (aa1049-1062) - LS-C108894 from LifeSpan Bioscience
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Anti-HIP1R Antibody - LS-C152864 from LifeSpan Bioscience
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HIP1 Related Antibody (1E1) - NB300-206 from Novus Biologicals
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HIP1 Related Antibody - NBP2-38391 from Novus Biologicals
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