Gene Symbol | HIP1R |
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Entrez Gene | 9026 |
Alt Symbol | HIP12, HIP3, ILWEQ |
Species | Human |
Gene Type | protein-coding |
Description | huntingtin interacting protein 1 related |
Other Description | HIP-12|HIP1-related protein|huntingtin interacting protein 12|huntingtin-interacting protein 1-related protein|huntingtin-interacting protein 12 |
Swissprots | A6NHQ6 Q9UED9 O75146 Q6NXG8 |
Accessions | EAW98346 EAW98347 O75146 AB013384 BAA33713 AB014555 BAA31630 AK024062 BAG51260 AK090537 BAG52180 AK295389 BAG58343 AK298387 BAG60622 AK307446 AK308538 AW962010 BC011354 BC038981 BC067085 AAH67085 CF454957 DA779723 DN999807 HY123489 XM_011538963 XP_011537265 XM_011538964 XP_011537266 NM_001303097 NP_001290026 NM_001303099 NP_001290028 NM_003959 NP_003950 |
Function | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. {ECO:0000269|PubMed:11889126, ECO:0000269|PubMed:14732715}. |
Subcellular Location | Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Note=Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region. |
Tissue Specificity | Brain, heart, kidney, pancreas, and liver, but not in lung or placenta. |
Human HIP1R full length protein - ab131891 from Abcam
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Human HIP1R peptide - ab86622 from Abcam
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HIP1R Antibody Blocking Peptide - LS-E752 from LifeSpan Bioscience
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HIP1R Antibody Blocking Peptide - LS-E26991 from LifeSpan Bioscience
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Recombinant Human HIP1 Related Protein - H00009026-P01 from Novus Biologicals
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Recombinant Human HIP1 Related Protein - H00009026-Q01 from Novus Biologicals
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HIP1R-Antibody-N-term-Blocking-peptide - BP11109a from Abgent, a WuXi AppTec company
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HIP1R blocking peptide - GTX88263-PEP from GeneTex
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HIP1R Peptide - AC21-1815-P from Abcore
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HIP12 / HIP1R - H00009026-P01-10 from Acris Antibodies
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HIP12 / HIP1R - H00009026-P01-25 from Acris Antibodies
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HIP12 / HIP1R - H00009026-Q01-10 from Acris Antibodies
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HIP12 / HIP1R - H00009026-Q01-25 from Acris Antibodies
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HIP1R Peptide - 42-228P from ProSci
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HIP1R fusion protein - Ag10353 from Proteintech Group
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HIP1R fusion protein - Ag10657 from Proteintech Group
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Recombinant Human HIP1R, His-tagged - HIP1R-29320TH from Creative Biomart
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Recombinant Human HIP1R, GST-tagged - HIP1R-13784H from Creative Biomart
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Recombinant Human HIP1R, GST-tagged - HIP1R-29H from Creative Biomart
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Recombinant Human HIP1R, MYC/DDK-tagged - HIP1R-30H from Creative Biomart
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Recombinant Huntingtin Interacting Protein 12 (HIP12) - RPC525Hu01 from Uscn Life Science Inc.
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Recombinant Huntingtin Interacting Protein 12 (HIP12) - RPC525Hu01 from Cloud-clone
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Recombinant Human Huntingtin-interacting protein 1-related protein(HIP1R) ,partial - CSB-YP010366HU CSB-EP010366HU CSB-BP010366HU CSB-MP010366HU from Cusabio
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HIP12 / HIP1R - TP316638 from Acris Antibodies
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HIP1R/ HIP12, Peptide - MBS426717 from MyBioSource
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