Gene Symbol | MXD4 |
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Entrez Gene | 10608 |
Alt Symbol | MAD4, MST149, MSTP149, bHLHc12 |
Species | Human |
Gene Type | protein-coding |
Description | MAX dimerization protein 4 |
Other Description | Mad4 homolog|class C basic helix-loop-helix protein 12|max dimerization protein 4|max dimerizer 4|max-associated protein 4|max-interacting transcriptional repressor MAD4 |
Swissprots | A2A335 Q5TZX4 Q14582 |
Accessions | CAA89217 EAW82530 EAW82531 EAW82532 EAW82533 EAW82534 EAW82535 EAW82536 Q14582 AF040963 AAB97009 AF082740 AAF98553 AF187724 AAQ13695 AK024501 BAB15791 AK026392 BC002713 AAH02713 BC028340 BC068060 AAH68060 BT019969 AAV38772 BT019970 AAV38773 XM_011513388 XP_011511690 XM_011513389 XP_011511691 XM_011513390 XP_011511692 XR_427467 XR_924911 XR_924912 NM_006454 NP_006445 |
Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Mad 4 (H-209) - sc-771 from Santa Cruz Biotechnology
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Mad 4 (N-19) - sc-1221 from Santa Cruz Biotechnology
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Anti-MAD4 antibody - ab111062 from Abcam
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Anti-MAD4 antibody - ab66367 from Abcam
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Anti-MAD4 antibody - ab15841 from Abcam
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Anti-MAD4 antibody - N-terminal - ab189783 from Abcam
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Anti-MXD4 Antibody (aa10-59) - LS-C119042 from LifeSpan Bioscience
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Anti-MXD4 Antibody (N-Terminus) - LS-C30609 from LifeSpan Bioscience
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Anti-MXD4 Antibody (aa212-224) - LS-C55080 from LifeSpan Bioscience
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Anti-MXD4 Antibody (N-Terminus) IHC-plus⢠- LS-B10844 from LifeSpan Bioscience
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MAD4 Antibody - NBP2-14803 from Novus Biologicals
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MAD4 Antibody - NB100-1117 from Novus Biologicals
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MAD4 Antibody - H00010608-B02 from Novus Biologicals
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Anti-MAD4/MXD4 antibody produced in goat - SAB2500612 from Sigma-Aldrich
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Anti-MXD4 antibody produced in rabbit - AV32777 from Sigma-Aldrich
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Anti-MAD4, N-Terminal antibody produced in rabbit - SAB4500135 from Sigma-Aldrich
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Anti-MXD4 antibody produced in mouse - SAB1407023 from Sigma-Aldrich
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MXD4 antibody - N-terminal region (ARP32777_P050) - ARP32777_P050 from Aviva Systems Biology
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MXD4 antibody - N-terminal region (ARP32777_T100) - ARP32777_T100 from Aviva Systems Biology
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MAD4--MXD4-Antibody - AF1645a from Abgent, a WuXi AppTec company
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MAD4 antibody [C2C3], C-term - GTX104828 from GeneTex
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MAD4 antibody, C-term - GTX15841 from GeneTex
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MAD4 antibody - GTX123154 from GeneTex
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MAD4 antibody - GTX123701 from GeneTex
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MXD4 Antibody (OAAF02432) - OAAF02432 from Aviva Systems Biology
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