Gene Symbol | MXD4 |
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Entrez Gene | 10608 |
Alt Symbol | MAD4, MST149, MSTP149, bHLHc12 |
Species | Human |
Gene Type | protein-coding |
Description | MAX dimerization protein 4 |
Other Description | Mad4 homolog|class C basic helix-loop-helix protein 12|max dimerization protein 4|max dimerizer 4|max-associated protein 4|max-interacting transcriptional repressor MAD4 |
Swissprots | A2A335 Q5TZX4 Q14582 |
Accessions | CAA89217 EAW82530 EAW82531 EAW82532 EAW82533 EAW82534 EAW82535 EAW82536 Q14582 AF040963 AAB97009 AF082740 AAF98553 AF187724 AAQ13695 AK024501 BAB15791 AK026392 BC002713 AAH02713 BC028340 BC068060 AAH68060 BT019969 AAV38772 BT019970 AAV38773 XM_011513388 XP_011511690 XM_011513389 XP_011511691 XM_011513390 XP_011511692 XR_427467 XR_924911 XR_924912 NM_006454 NP_006445 |
Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. |
Human MAD4 full length protein - ab161066 from Abcam
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MAD4 peptide - ab45479 from Abcam
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MXD4 Antibody Blocking Peptide - LS-E25432 from LifeSpan Bioscience
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MXD4 Antibody Blocking Peptide - LS-E11533 from LifeSpan Bioscience
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Recombinant Human MAD4 Protein - H00010608-P01 from Novus Biologicals
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MAD4/MXD4 blocking peptide - GTX15841-PEP from GeneTex
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MAD4 Peptide - AC21-0260-P from Abcore
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MAD4 - H00010608-P01-02 from Acris Antibodies
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MAD4 Peptide - 45-855P from ProSci
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MXD4 fusion protein - ag10181 from Proteintech Group
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MXD4 fusion protein - Ag10311 from Proteintech Group
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Recombinant MAD4 protein - 31248 from ActiveMotif
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Recombinant Human MXD4, GST-tagged - MXD4-1119H from Creative Biomart
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Recombinant Human Max dimerization protein 4(MXD4) - CSB-YP015253HU CSB-EP015253HU CSB-BP015253HU CSB-MP015253HU from Cusabio
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MAD4 (full length, N-term HIS tag) - TP760343 from Acris Antibodies
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MAD4/MXD4, Peptide - MBS426606 from MyBioSource
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MXD4-Antibody-C-term-Blocking-Peptide - BP6539b from Abgent, a WuXi AppTec company
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MXD4-Antibody-N-term-Blocking-Peptide - BP6539a from Abgent, a WuXi AppTec company
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MXD4 Peptide, Human - M34GP09957H from Creative Peptides
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MAD4 Recombinant Protein Antigen - NBP2-58767PEP from Novus Biologicals
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Max dimerization protein 4 (MXD4), Recombinant Protein - MBS1279374 from MyBioSource
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MXD4 Immunizing peptide - orb17175 from Biorbyt
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