| Gene Symbol |
MXD4
|
| Entrez Gene |
10608
|
| Alt Symbol |
MAD4, MST149, MSTP149, bHLHc12
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAX dimerization protein 4
|
| Other Description |
Mad4 homolog|class C basic helix-loop-helix protein 12|max dimerization protein 4|max dimerizer 4|max-associated protein 4|max-interacting transcriptional repressor MAD4
|
| Swissprots |
A2A335 Q5TZX4 Q14582
|
| Accessions |
CAA89217 EAW82530 EAW82531 EAW82532 EAW82533 EAW82534 EAW82535 EAW82536 Q14582 AF040963 AAB97009 AF082740 AAF98553 AF187724 AAQ13695 AK024501 BAB15791 AK026392 BC002713 AAH02713 BC028340 BC068060 AAH68060 BT019969 AAV38772 BT019970 AAV38773 XM_011513388 XP_011511690 XM_011513389 XP_011511691 XM_011513390 XP_011511692 XR_427467 XR_924911 XR_924912 NM_006454 NP_006445
|
| Function |
Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
|