MTAP

Gene Symbol	MTAP
Entrez Gene	4507
Alt Symbol	BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus
Species	Human
Gene Type	protein-coding
Description	methylthioadenosine phosphorylase
Other Description	5'-methylthioadenosine phosphorylase|MTA phosphorylase|MTAPase|MeSAdo phosphorylase|S-methyl-5'-thioadenosine phosphorylase|epididymis luminal protein 249
Swissprots	Q5T3P3 Q9H010 I2G7M5 I2G7N0 I2G7M7 I2G7M9 Q13126 I2G7M8 I2G7M6
Accessions	AAR24607 BAD60918 EAW58605 EAW58606 Q13126 AB062485 BAB93510 AF109294 AAD19641 AF216650 AAF82688 AK024734 AK300592 BAG62290 AK309365 AY712791 AAU04442 BC012316 AAH12316 BC018625 AAH18625 BC026106 AAH26106 BG576334 BM994282 BQ220538 BQ232183 CA440131 CR541670 CAG46471 CR541710 CAG46511 FJ224338 ACI46030 HE654772 CCF77345 HE654773 CCF77346 HE654774 CCF77347 HE654775 CCF77348 HE654776 CCF77349 HE654777 CCF77350 JF432462 ADZ15679 L40432 AAG38871 U22233 AAA81646 NM_002451 NP_002442
Function	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates. {ECO:0000255|HAMAP-Rule:MF_03155, ECO:0000269|PubMed:3091600}.
Subcellular Location	Cytoplasm. Nucleus {ECO:0000255|HAMAP- Rule:MF_03155}.
Tissue Specificity	Ubiquitously expressed.
Top Pathways	Cysteine and methionine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-MTAP-cDNA-Clone - DC05571 from Abgent, a WuXi AppTec company Prices $382.05 Sizes 10 µg Species Human Accession BC026106

MTAP - MBS1270433 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC026106

MTAP - MBS1275903 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC018625

Human MTAP cDNA clone(NM_002451.3) - CDFH011845 from Creative Biomart Species Human Accession NM_002451.3

Human MTAP ORF clone(NM_002451.3) - CDCL185410 from Creative Biomart Species Human Accession NM_002451.3

Human MTAP ORF Clone(NM_002451.3) - CDCR283116 from Creative Biomart Species Human Accession NM_002451.3

Human MTAP ORF Clone(NM_002451.3) - CDCR283117 from Creative Biomart Species Human Accession NM_002451.3

Human MTAP Gene ORF cDNA clone in cloning vector - HG11417-G from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11417-ACG from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, C-His tag - HG11417-CH from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, N-His tag - HG11417-NH from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11417-ANG from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11417-NF from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11417-NM from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11417-CF from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11417-CM from Sino Biological Species Human

Human MTAP Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11417-G-N from Sino Biological Species Human Accession NM_002451.3

Human MTAP Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11417-ACR from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11417-ANR from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, N-HA tag - HG11417-NY from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid, C-HA tag - HG11417-CY from Sino Biological Species Human

Human MTAP Gene ORF cDNA clone expression plasmid - HG11417-UT from Sino Biological Species Human

Human MTAP ORF clone(NM_002451.3) - CDCL185410 from Creative biogene Species Human

Human MTAP ORF Clone (BC018625) - CDCS410802 from Creative biogene Species Human Accession Q13126

Human MTAP ORF Clone (BC026106) - CDCS410803 from Creative biogene Species Human Accession Q13126

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