MTAP

Gene Symbol	MTAP
Entrez Gene	4507
Alt Symbol	BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus
Species	Human
Gene Type	protein-coding
Description	methylthioadenosine phosphorylase
Other Description	5'-methylthioadenosine phosphorylase|MTA phosphorylase|MTAPase|MeSAdo phosphorylase|S-methyl-5'-thioadenosine phosphorylase|epididymis luminal protein 249
Swissprots	Q5T3P3 Q9H010 I2G7M5 I2G7N0 I2G7M7 I2G7M9 Q13126 I2G7M8 I2G7M6
Accessions	AAR24607 BAD60918 EAW58605 EAW58606 Q13126 AB062485 BAB93510 AF109294 AAD19641 AF216650 AAF82688 AK024734 AK300592 BAG62290 AK309365 AY712791 AAU04442 BC012316 AAH12316 BC018625 AAH18625 BC026106 AAH26106 BG576334 BM994282 BQ220538 BQ232183 CA440131 CR541670 CAG46471 CR541710 CAG46511 FJ224338 ACI46030 HE654772 CCF77345 HE654773 CCF77346 HE654774 CCF77347 HE654775 CCF77348 HE654776 CCF77349 HE654777 CCF77350 JF432462 ADZ15679 L40432 AAG38871 U22233 AAA81646 NM_002451 NP_002442
Function	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates. {ECO:0000255|HAMAP-Rule:MF_03155, ECO:0000269|PubMed:3091600}.
Subcellular Location	Cytoplasm. Nucleus {ECO:0000255|HAMAP- Rule:MF_03155}.
Tissue Specificity	Ubiquitously expressed.
Top Pathways	Cysteine and methionine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MTAP full length protein - ab132580 from Abcam Category Protein Source Wheat germ Species Human

Human MTAP full length protein - ab132581 from Abcam Category Protein Source Wheat germ Species Human

Human MTAP protein fragment - ab80284 from Abcam Category Protein Source E. coli Species Human

Recombinant Human MTAP Protein - H00004507-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MTAP Protein - H00004507-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MTAP Protein - H00004507-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MTAP Protein - GTX109117-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

MTAP - H00004507-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

MTAP - H00004507-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MTAP - H00004507-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MTAP - H00004507-P02 from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Species Human

MTAP - H00004507-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MTAP - H00004507-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MTAP - H00004507-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MTAP - H00004507-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MTAP fusion protein - Ag17954 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

MTAP fusion protein - Ag2051 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

MTAP fusion protein - Ag24475 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

MTAP, Active Human Recombinant Protein - GWB-C6140F from Genway Biotech Category Protein Prices $600.00 Sizes 50 µg Species Human

Recombinant Human Methylthioadenosine Phosphorylase, GST-tagged - MTAP-422H from Creative Biomart Category Protein Source E. coli.

Recombinant Human MTAP, GST-tagged - MTAP-29502TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Methylthioadenosine Phosphorylase (MTAP) - RPG011Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Methylthioadenosine Phosphorylase (MTAP) - RPG011Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Methylthioadenosine Phosphorylase (MTAP) - RPG011Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Methylthioadenosine Phosphorylase (MTAP) - RPG011Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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