STIL

Gene Symbol STIL
Entrez Gene 6491
Alt Symbol MCPH7, SIL
Species Human
Gene Type protein-coding
Description SCL/TAL1 interrupting locus
Other Description SCL-interrupting locus protein|TAL-1-interrupting locus protein
Swissprots Q5T0C5 Q68CN9 Q15468
Accessions AAK51418 CAI19730 CAI19731 CAI19732 CAI19733 EAX06872 EAX06873 EAX06874 Q15468 AA897748 AK098445 AK128406 AK307519 BC053615 AAH53615 BC126223 AAI26224 BC136432 BC144089 AAI44090 CR749851 CAH18699 DA754072 DB062060 DB062487 HQ258539 ADR83293 M74558 AAA60550 XM_006710834 XP_006710897 XM_011541991 XP_011540293 XM_011541992 XP_011540294 XM_011541993 XP_011540295 XM_011541994 XP_011540296 XM_011541995 XP_011540297 XM_011541996 XP_011540298 XM_011541997 XP_011540299 XM_011541998 XP_011540300 XM_011541999 XP_011540301 XM_011542000 XP_011540302 XM_011542001 XP_011540303 XR_946746 NM_001048166 NP_001041631 NM_001282936 NP_001269865 NM_001282937 NP_001269866 NM_001282938 NP_001269867 NM_001282939 NP_001269868 NM_003035 NP_003026
Function Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation; its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Plays a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1. {ECO:0000269|PubMed:16024801, ECO:0000269|PubMed:9372240}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}.
Tissue Specificity Expressed in all hematopoietic tissues and cell lines. Highly expressed in a variety of tumors characterized by increased mitotic activity with highest expression in lung cancer. {ECO:0000269|PubMed:15107824, ECO:0000269|PubMed:1922059}.

Sil (A-6) - sc-271910 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sil (A-6): sc-271910. Western blot analysis of Sil expression in HEL 92.1.7 (A), K-562 (B), Jurkat (C) and ALL-SIL (D) whole cell lysates.

Sil (C-18) - sc-32620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Sil (T-16) - sc-32619 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Sil (T-16): sc-32619. Western blot analysis of Sil expression in K-562 (A) and HEL 92.1.7 (B) whole cell lysates.

Anti-STIL antibody - ab89314 from Abcam

Prices $370.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STIL antibody (ab89314) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-STIL antibody - ab110797 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STIL antibody (ab110797) at 1 µg/ml (Please Milk block 3%)Lane 1 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLane 2 : THP1 (Human acute monocytic leukemia cell line) Whole Cell LysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-STIL Antibody (aa450-500) - LS-C289177 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-STIL Antibody (aa1237-1287) - LS-C289176 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse SIL by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-SIL antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

STIL Polyclonal Antibody - bs-9303R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Paraformaldehyde-fixed, paraffin embedded Rat testis tissue; Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with STIL Polyclonal Antibody, Unconjugated (bs-9303R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining

STIL Antibody - N-terminal region (ARP75124_P050) - ARP75124_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL antibody (FITC) - orb3398 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

STIL / SIL antibody - H00006491-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Anti-STIL (C-terminal) polyclonal antibody - DPABH-00595 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-STIL (aa 1050-1150) polyclonal antibody - DPABH-21951 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

SIL Antibody - A302-441A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

SIL Antibody - A302-442A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (0.2 mg/ml)
Host Rabbit
Clonality Polyclonal

SIL Antibody AbVantage™ Pack - A310-885A from Bethyl Labs

Prices $472.00
Sizes 1 pack
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-9303R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-9303R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-9303R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-9303R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, Cy3 Conjugated - bs-9303R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, Cy5 Conjugated - bs-9303R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, Cy5.5 Conjugated - bs-9303R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, Cy7 Conjugated - bs-9303R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

STIL Polyclonal Antibody, FITC Conjugated - bs-9303R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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