PREX2

Gene Symbol PREX2
Entrez Gene 80243
Alt Symbol 6230420N16Rik, DEP.2, DEPDC2, P-REX2, PPP1R129
Species Human
Gene Type protein-coding
Description phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Other Description DEP domain-containing protein 2|PtdIns(3,4,5)-dependent Rac exchanger 2|phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein|protein phosphatase 1, regulatory subunit 129
Swissprots Q6R7Q3 B4DFX0 Q70Z35 Q32KL0 Q9H805 Q9H961 Q6R7Q4 Q32KL1
Accessions Q70Z35 AJ437636 CAD26885 AK023049 BAB14375 AK024079 AK294299 BAG57581 AY508996 AAS82571 AY508997 AAS82572 AY570973 AAS59407 BC146369 AAI46370 BC148795 AAI48796 BK005160 DAA05333 BK005161 DAA05334 XM_011517612 XP_011515914 NM_024870 NP_079146 NM_025170 NP_079446
Function Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase. {ECO:0000269|PubMed:15304342, ECO:0000269|PubMed:15304343, ECO:0000269|PubMed:15897194}.
Tissue Specificity Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart. {ECO:0000269|PubMed:15304343}.

Human DEPDC2 ELISA Kit (Sandwich ELISA) - LS-F12401 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 78
Range 78-5000 pg/ml

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein, PREX2, Human, ELISA Kit - E4467h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t
Range 78-5000 pg/mL

phosphatidylinositol-3, 4, 5-trisphosphate-dependent Rac exchange factor 2, ELISA Kit - MBS9317181 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse DEPDC2 ELISA Kit (Custom ELISA) - LS-F19932 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 78-5000 pg/ml

PREX2 - EKH4584 from Nordic BioSite

Sensitivity 46.9pg/ml
Range 78-5000pg/ml

PREX2 ELISA Kit (Human) (OKEH01730) - OKEH01730 from Aviva Systems Biology

Category ELISA Kit
Prices $450.00
Sizes 96 wells
Sensitivity < 34 pg/mL
Range 78 - 5,000 pg/mL

Human PREX2 ELISA Kit - E028918 from Biobool

Category ELISA Kit
Sensitivity <46.9pg/ml

Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein ELISA Kit - EK4634 from Signalway Antibody

Category ELISA Kit
Prices $659.00
Sizes 1x96t
Sensitivity less than 15pg/mL
Range 31.2-2000 pg/mL

Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2) ELISA Kit - AE26045HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t

Phosphatidylinositol 3, 4, 5-trisphosphate-dependent Rac exchanger 2 protein, ELISA Kit - MBS9428460 from MyBioSource

Category ELISA Kit
Prices $605.00
Sizes 96 tests
Sensitivity Less than 34pg/mL
Range 78-5000 pg/mL

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein, ELISA Kit - MBS2881972 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 78-5000 pg/mL

Human DEPDC2 ELISA Kit (Sandwich ELISA) - LS-F34177 from LifeSpan Bioscience

Category ELISA Kit
Sensitivity 46.9
Range 78-5000 pg/ml
Search more