HIST2H2AB

Gene Symbol HIST2H2AB
Entrez Gene 317772
Alt Symbol H2AB
Species Human
Gene Type protein-coding
Description histone cluster 2, H2ab
Other Description histone 2, H2ab|histone H2A type 2-B
Swissprots Q8IUE6
Accessions AAN59958 CAI12570 EAW53603 Q8IUE6 BC172330 AAI72330 NM_175065 NP_778235
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular Location Nucleus. Chromosome.
Top Pathways Systemic lupus erythematosus, Alcoholism

Panoply™ Human HIST2H2AB Knockdown Stable Cell Line - CSC-DC007064 from Creative biogene

Category Cell Line
Species Human
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