Gene Symbol | HIST2H2AB |
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Entrez Gene | 317772 |
Alt Symbol | H2AB |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 2, H2ab |
Other Description | histone 2, H2ab|histone H2A type 2-B |
Swissprots | Q8IUE6 |
Accessions | AAN59958 CAI12570 EAW53603 Q8IUE6 BC172330 AAI72330 NM_175065 NP_778235 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
HIST2H2AB Antibody Blocking Peptide - LS-E2633 from LifeSpan Bioscience
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HIST2H2AB-Antibody-N-term-Blocking-peptide - BP13703a from Abgent, a WuXi AppTec company
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Recombinant Human Histone H2A type 2-B(HIST2H2AB) - CSB-YP816874HU CSB-EP816874HU CSB-BP816874HU CSB-MP816874HU from Cusabio
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Histone cluster 2, H2ab (HIST2H2AB) - TP320685 from Acris Antibodies
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HIST2H2AB Peptide, Human - M34GP07064H from Creative Peptides
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Histone H2A type 2-B (HIST2H2AB), Recombinant Protein - MBS1485289 from MyBioSource
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