DOK7

Gene Symbol	DOK7
Entrez Gene	285489
Alt Symbol	C4orf25, CMS1B
Species	Human
Gene Type	protein-coding
Description	docking protein 7
Other Description	downstream of tyrosine kinase 7|protein Dok-7
Swissprots	Q86XG5 Q8NBC1 Q6P6A6 A2A499 A2RRD4 Q18PE1 Q8N2J3 E9PB56
Accessions	EAW82463 Q18PE1 AB220918 BAE96739 AK075037 BAC11367 AK091037 BAC03572 AK096456 BAC04795 BC043568 AAH43568 BC062369 AAH62369 BC131544 AAI31545 BC141852 AAI41853 BM684814 DA205628 DA823926 XM_011513435 XP_011511737 XM_011513436 XP_011511738 XM_011513437 XP_011511739 NM_001164673 NP_001158145 NM_001256896 NP_001243825 NM_001301071 NP_001288000 NM_173660 NP_775931
Function	Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. {ECO:0000269|PubMed:20603078}.
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Accumulates at neuromuscular junctions. {ECO:0000250}.
Tissue Specificity	Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level). {ECO:0000269|PubMed:16794080}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Dok-7 (A-7) - sc-390856 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Dok-7 (P-19) - sc-55168 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Dok-7 (H-284) - sc-50463 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Dok-7 (H-77) - sc-50464 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Dok-7 (S-17) - sc-55169 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

p-Dok-7 (Tyr 395) - sc-68691 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

p-Dok-7 (Tyr 405) - sc-68692 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-DOK7 antibody - ab75049 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DOK7 antibody - ab197313 from Abcam Prices $370.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 antibody - ab77371 from Abcam Prices $370.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (clone 1F7) - LS-C337744 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1F7

Anti-DOK7 Antibody (clone 1A9) - LS-C337748 from LifeSpan Bioscience Prices $350.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 1A9

Anti-DOK7 Antibody (clone 4C6) - LS-C337746 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4C6

Anti-DOK7 Antibody (clone 7E2) - LS-C173991 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 7E2

Anti-DOK7 Antibody (clone 5G8) - LS-C337753 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 5G8

Anti-DOK7 Antibody (aa26-55, APC) - LS-C234738 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa26-55, Biotin) - LS-C234739 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa26-55, AP) - LS-C234740 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa402-451) - LS-C145325 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa26-55, FITC) - LS-C234742 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa26-55, PE) - LS-C234746 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa26-55, Azide-free, HRP) - LS-C249863 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa25-55) - LS-C320929 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (aa26-55) - LS-C167503 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-DOK7 Antibody (clone 5C6) - LS-C173981 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 5C6

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