DOK7

Gene Symbol	DOK7
Entrez Gene	285489
Alt Symbol	C4orf25, CMS1B
Species	Human
Gene Type	protein-coding
Description	docking protein 7
Other Description	downstream of tyrosine kinase 7|protein Dok-7
Swissprots	Q86XG5 Q8NBC1 Q6P6A6 A2A499 A2RRD4 Q18PE1 Q8N2J3 E9PB56
Accessions	EAW82463 Q18PE1 AB220918 BAE96739 AK075037 BAC11367 AK091037 BAC03572 AK096456 BAC04795 BC043568 AAH43568 BC062369 AAH62369 BC131544 AAI31545 BC141852 AAI41853 BM684814 DA205628 DA823926 XM_011513435 XP_011511737 XM_011513436 XP_011511738 XM_011513437 XP_011511739 NM_001164673 NP_001158145 NM_001256896 NP_001243825 NM_001301071 NP_001288000 NM_173660 NP_775931
Function	Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. {ECO:0000269|PubMed:20603078}.
Subcellular Location	Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Accumulates at neuromuscular junctions. {ECO:0000250}.
Tissue Specificity	Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level). {ECO:0000269|PubMed:16794080}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DOK7 peptide - ab90998 from Abcam Category Peptide

DOK7 Antibody Blocking Peptide - LS-E2532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK7 Antibody Blocking Peptide - LS-E22563 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DOK7-Antibody-N-term-Blocking-peptide - BP13568a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DOK7 Blocking Peptide - 33R-7809 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DOK7 fusion protein - ag18543 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DOK7 fusion protein - ag18627 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Docking Protein 7 (DOK7) - RPF377Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Human Protein Dok-7(DOK7) - CSB-YP623281HU CSB-EP623281HU CSB-BP623281HU CSB-MP623281HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DOK7 - TP319267 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DOK7 Recombinant Protein Antigen - NBP2-32465PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DOK7 Blocking Peptide - abx061226 from Abbexa Category Peptide Species Human, Mouse

DOK7 Peptide, Human - M34GP04489H from Creative Peptides Category Peptide Source Synthetic. Species Human

DOK7 Blocking Peptide - CBP5139 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

DOK7 peptide - orb319285 from Biorbyt Category Peptide Prices $247.00, $510.00 Sizes 1 mg, 5 mg

Protein Dok-7 (DOK7), Recombinant Protein - MBS1311800 from MyBioSource Category Protein Prices $1,290.00, $1,290.00, $1,510.00, $1,510.00, $2,120.00, $2,120.00, $2,585.00, $2,585.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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