| Gene Symbol | DOK7 |
|---|---|
| Entrez Gene | 285489 |
| Alt Symbol | C4orf25, CMS1B |
| Species | Human |
| Gene Type | protein-coding |
| Description | docking protein 7 |
| Other Description | downstream of tyrosine kinase 7|protein Dok-7 |
| Swissprots | Q86XG5 Q8NBC1 Q6P6A6 A2A499 A2RRD4 Q18PE1 Q8N2J3 E9PB56 |
| Accessions | EAW82463 Q18PE1 AB220918 BAE96739 AK075037 BAC11367 AK091037 BAC03572 AK096456 BAC04795 BC043568 AAH43568 BC062369 AAH62369 BC131544 AAI31545 BC141852 AAI41853 BM684814 DA205628 DA823926 XM_011513435 XP_011511737 XM_011513436 XP_011511738 XM_011513437 XP_011511739 NM_001164673 NP_001158145 NM_001256896 NP_001243825 NM_001301071 NP_001288000 NM_173660 NP_775931 |
| Function | Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. {ECO:0000269|PubMed:20603078}. |
| Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Accumulates at neuromuscular junctions. {ECO:0000250}. |
| Tissue Specificity | Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level). {ECO:0000269|PubMed:16794080}. |
Mouse/Human DOK7 ELISA Kit (Cell-Based ELISA) - LS-F3223 from LifeSpan Bioscience
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DOK7 Colorimetric Cell-Based ELISA - CB6044 from Assay Biotechnology
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docking protein 7, ELISA Kit - MBS9319023 from MyBioSource
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Docking Protein 7 (DOK7), ELISA Kit - MBS9313348 from MyBioSource
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DOK7 ELISA Kit - DEIA-XYA556 from Creative Diagnostics
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Human DOK7 ELISA Kit - E012260 from Biobool
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DOK7 Colorimetric Cell-Based ELISA Kit - EKA50873 from Biomatik
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