Gene Symbol | PTGIS |
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Entrez Gene | 5740 |
Alt Symbol | CYP8, CYP8A1, PGIS, PTGI |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin I2 (prostacyclin) synthase |
Other Description | cytochrome P450, family 8, subfamily A, polypeptide 1|prostacyclin synthase|prostaglandin I2 synthase |
Swissprots | Q3MII8 Q9HAX3 Q9HAX4 Q16647 Q9HAX2 |
Accessions | BAA11910 BAA28219 CCQ43002 EAW75655 Q16647 AF297048 AAG31781 AF297049 AAG31782 AF297050 AAG31783 AF297051 AAG31784 AF297052 AAG31785 AK055640 BC101809 AAI01810 BC101811 AAI01812 BC143381 D38145 BAA07343 NM_000961 NP_000952 |
Function | Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2). |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. |
Tissue Specificity | Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate. |
Top Pathways | Arachidonic acid metabolism |
Human PTGIS full length protein - ab114517 from Abcam
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Human PTGIS protein fragment - ab114516 from Abcam
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PTGIS peptide - ab187257 from Abcam
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PGIS / PTGIS Antibody Blocking Peptide - LS-E16301 from LifeSpan Bioscience
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PGIS / PTGIS Antibody Blocking Peptide - LS-E9412 from LifeSpan Bioscience
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PGIS / PTGIS Antibody Blocking Peptide - LS-E9413 from LifeSpan Bioscience
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Prostaglandin I2 Synthase Partial Recombinant Protein - H00005740-Q01 from Novus Biologicals
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Recombinant Human Prostaglandin I2 Synthase Protein - H00005740-P01 from Novus Biologicals
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CYP8A1-Antibody-C-term-Blocking-Peptide - BP7997b from Abgent, a WuXi AppTec company
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CYP8A1-Antibody-N-term-Blocking-Peptide - BP7997a from Abgent, a WuXi AppTec company
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PTGIS Blocking Peptide - 33R-2493 from Fitzgerald
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PTGIS - H00005740-P01 from Acris Antibodies
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PTGIS - H00005740-Q01-10 from Acris Antibodies
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PTGIS - H00005740-Q01-25 from Acris Antibodies
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PTGIS fusion protein - ag13389 from Proteintech Group
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Recombinant Human PTGIS - PTGIS-30324TH from Creative Biomart
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Recombinant Human PTGIS - PTGIS-30325TH from Creative Biomart
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Recombinant Prostaglandin I Synthase (PTGIS) - RPA740Hu01 from Uscn Life Science Inc.
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Recombinant Prostaglandin I Synthase (PTGIS) - RPA740Hu01 from Cloud-clone
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Recombinant Human Prostacyclin synthase(PTGIS) - CSB-YP624112HU CSB-EP624112HU CSB-BP624112HU CSB-MP624112HU from Cusabio
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PTGIS - TP311030 from Acris Antibodies
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Prostacyclin synthase (PTGIS), Recombinant Protein - MBS1442657 from MyBioSource
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Prostaglandin I2 Synthase Recombinant Protein Antigen - NBP1-85359PEP from Novus Biologicals
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PTGIS Peptide, Human - M34GP12668H from Creative Peptides
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PTGIS Recombinant Protein (OPCD06480) - OPCD06480 from Aviva Systems Biology
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